Regulatory Status
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Safety Data
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Safety Opinions
Official safety assessments from the Scientific Committee on Consumer Safety (SCCS) and Cosmetic Ingredient Review (CIR).
ngredients, and concluded that seven alkane diols are safe in cosmetics in the present practices of use and concentration described in this safety assessment, but that the available data are insufficient to make a determination of safety for three ingredients, namely 1,4-Butanediol, 2,3-Bu- taned
ngredients, and concluded that seven alkane diols are safe in cosmetics in the present practices of use and concentration described in this safety assessment, but that the available data are insufficient to make a determination of safety for three ingredients, namely 1,4-Butanediol, 2,3-Bu- taned
ngredients, and concluded that seven alkane diols are safe in cosmetics in the present practices of use and concentration described in this safety assessment, but that the available data are insufficient to make a determination of safety for three ingredients, namely 1,4-Butanediol, 2,3-Bu- taned
ngredients, and concluded that seven alkane diols are safe in cosmetics in the present practices of use and concentration described in this safety assessment, but that the available data are insufficient to make a determination of safety for three ingredients, namely 1,4-Butanediol, 2,3-Bu- taned
ngredients, and concluded that seven alkane diols are safe in cosmetics in the present practices of use and concentration described in this safety assessment, but that the available data are insufficient to make a determination of safety for three ingredients, namely 1,4-Butanediol, 2,3-Bu- taned
Expert Verdict
Propanediol (CAS 504-63-2) is permitted without restriction under EU Cosmetics Regulation 1223/2009 and holds FDA GRAS status (GRN No. 302, 2009), with a wide margin of safety for cosmetic use up to 39.9%, minimal dermal absorption (0.12% at 48h), and a clean sensitization profile.
Regulatory Flags
Frequently Asked Questions
Is Propanediol safe in cosmetics?
Propanediol (CAS 504-63-2) is permitted without restriction under EU Cosmetics Regulation 1223/2009 and holds FDA GRAS status (GRN No. 302, 2009), with a wide margin of safety for cosmetic use up to 39.9%, minimal dermal absorption (0.12% at 48h), and a clean sensitization profile. The EU classifies Propanediol as "permitted". Safety rating: EXCELLENT. This ingredient has been reviewed by cir.
Is Propanediol allowed in the EU?
Propanediol EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.
What does Propanediol do in cosmetics?
Propanediol functions as: Humectant; solvent; antimicrobial contributor; water activity reduction agent; self-preservation contributor. It is classified as a Humectant in our database. CAS number: 504-63-2.
What is the Margin of Safety for Propanediol?
adequate The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.
Compliance Tools
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Related Ingredients
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