Thiabendazole

INCI: THIABENDAZOLE

CAS Number
148-79-8
Function
Preservative, antifungal agent (benzimidazole fungicide)
Safety Rating
POOR

Regulatory Status

๐Ÿ‡ช๐Ÿ‡บ EU Status prohibited
๐Ÿ‡บ๐Ÿ‡ธ US Status permitted
US Notes FDA-approved as an antifungal drug (OTC/Rx); NOT listed as a permitted cosmetic preservative; cosmetic use would be off-label

For full compliance data across 55 jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety (MoS)
not established
Dermal Absorption
moderate
Sensitization
moderate

Calculate MoS for your specific formulation with the MoS Calculator.

Expert Verdict

CRITICAL: Banned in EU cosmetics (Annex II) . Classified as a pesticide active substance under EU Regulation. Reproductive toxicity concerns. Not a viable cosmetic ingredient in any major market. Do NOT formulate

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Concern Level: High

Regulatory Flags

preservative

Frequently Asked Questions

Is Thiabendazole safe in cosmetics?

CRITICAL: Banned in EU cosmetics (Annex II) . Classified as a pesticide active substance under EU Regulation. Reproductive toxicity concerns. Not a viable cosmetic ingredient in any major market. Do NOT formulate The EU classifies Thiabendazole as "prohibited". Safety rating: POOR.

Is Thiabendazole allowed in the EU?

Thiabendazole EU regulatory status: prohibited. This is based on EU Regulation 1223/2009 and its amendments.

What does Thiabendazole do in cosmetics?

Thiabendazole functions as: Preservative, antifungal agent (benzimidazole fungicide). It is classified as a cosmetic ingredient in our database. CAS number: 148-79-8.

What is the Margin of Safety for Thiabendazole?

not established The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.

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