Regulatory Status
For full compliance data across 55 jurisdictions, use the Substance Compliance tool.
Safety Data
Calculate MoS for your specific formulation with the MoS Calculator.
Toxicological Studies
10 study endpoints found for Uvinul A Plus. NOAEL (No Observed Adverse Effect Level) values are used to calculate the Margin of Safety per SCCS methodology.
| Endpoint | Value | Route | Species | Study Type | Source |
|---|---|---|---|---|---|
| NOAEL | 200 mg/kg bw/day | oral | rat | Developmental | COSMOS_DB |
| LOAEL | 1000 mg/kg bw/day | oral | rat | Developmental | COSMOS_DB |
| NOAEL | 500 mg/kg bw/day | oral | rat | oral | REACH |
| NOAEL | 250 mg/kg bw/day | oral | rabbit | oral | REACH |
| NOAEL | 742.119995117 mg/kg bw/day | oral | rat | oral | REACH |
| NOAEL | 742.119995117 mg/kg bw/day | oral | rat | oral | REACH |
| NOAEL | >=15000 ppm | oral | rat | oral | REACH |
| NOAEL | 5 mg/kg bw/day | - | - | reproductive | SCCS_PDF_extraction |
| NOAEL | 2.5 mg/kg bw/day | dermal | - | - | SCCS_PDF_extraction |
| NOAEL | 5 mg/kg bw/day | oral | - | reproductive | SCCS_PDF_extraction |
Safety Opinions
Official safety assessments from the Scientific Committee on Consumer Safety (SCCS) and Cosmetic Ingredient Review (CIR).
Expert Verdict
Good safety profile. Generally considered safe for cosmetic use.
Regulatory Flags
Frequently Asked Questions
Is Uvinul A Plus safe in cosmetics?
Good safety profile. Generally considered safe for cosmetic use. The EU classifies Uvinul A Plus as "permitted". Safety rating: GOOD. 10 toxicological study endpoint(s) are available in our database. This ingredient has been reviewed by sccs.
Is Uvinul A Plus allowed in the EU?
Uvinul A Plus EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.
What does Uvinul A Plus do in cosmetics?
Uvinul A Plus functions as: UV Filter. It is classified as a UV Filter / Sunscreen in our database. CAS number: 302776-68-7.
What is the Margin of Safety for Uvinul A Plus?
not established The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.
What is the NOAEL for Uvinul A Plus?
The NOAEL (No Observed Adverse Effect Level) for Uvinul A Plus is 200 mg/kg bw/day based on a Developmental study via oral route in rat. A total of 10 study endpoints are available. Source: COSMOS_DB.
Compliance Tools
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