Diethylamino Hydroxybenzoyl Hexyl Benzoate
INCI: DIETHYLAMINO HYDROXYBENZOYL HEXYL BENZOATE
Regulatory Status
For full compliance data across 55 jurisdictions, use the Substance Compliance tool.
Safety Data
Calculate MoS for your specific formulation with the MoS Calculator.
Toxicological Studies
10 study endpoints found for Diethylamino Hydroxybenzoyl Hexyl Benzoate. NOAEL (No Observed Adverse Effect Level) values are used to calculate the Margin of Safety per SCCS methodology.
| Endpoint | Value | Route | Species | Study Type | Source |
|---|---|---|---|---|---|
| NOAEL | 200 mg/kg bw/day | oral | rat | Developmental | COSMOS_DB |
| LOAEL | 1000 mg/kg bw/day | oral | rat | Developmental | COSMOS_DB |
| NOAEL | 500 mg/kg bw/day | oral | rat | oral | REACH |
| NOAEL | 250 mg/kg bw/day | oral | rabbit | oral | REACH |
| NOAEL | 742.119995117 mg/kg bw/day | oral | rat | oral | REACH |
| NOAEL | 742.119995117 mg/kg bw/day | oral | rat | oral | REACH |
| NOAEL | >=15000 ppm | oral | rat | oral | REACH |
| NOAEL | 5 mg/kg bw/day | - | - | reproductive | SCCS_PDF_extraction |
| NOAEL | 2.5 mg/kg bw/day | dermal | - | - | SCCS_PDF_extraction |
| NOAEL | 5 mg/kg bw/day | oral | - | reproductive | SCCS_PDF_extraction |
Safety Opinions
Official safety assessments from the Scientific Committee on Consumer Safety (SCCS) and Cosmetic Ingredient Review (CIR).
Sensitization Profile
Contact sensitization data for Diethylamino Hydroxybenzoyl Hexyl Benzoate based on clinical patch test studies and IFRA standards.
Source: SCCS
Expert Verdict
Broad-spectrum UVA filter also known as Bemotrizinol or Tinosorb A2B. Inherently photostable and maintains SPF values and critical wavelength after water immersion, making it well-suited for water-resistant sunscreen formulations. Approved and widely used internationally for years. FDA issued proposed order December 2025 to authorize at ≤6% in OTC sunscreens under Monograph M020 amendment. EU approved at up to 10%. Excellent safety and efficacy profile.
Regulatory Flags
Frequently Asked Questions
Is Diethylamino Hydroxybenzoyl Hexyl Benzoate safe in cosmetics?
Broad-spectrum UVA filter also known as Bemotrizinol or Tinosorb A2B. Inherently photostable and maintains SPF values and critical wavelength after water immersion, making it well-suited for water-resistant sunscreen formulations. Approved and widely used internationally for years. FDA issued proposed order December 2025 to authorize at ≤6% in OTC sunscreens under Monograph M020 amendment. EU approved at up to 10%. Excellent safety and efficacy profile. The EU classifies Diethylamino Hydroxybenzoyl Hexyl Benzoate as "permitted". Safety rating: GOOD. 10 toxicological study endpoint(s) are available in our database. This ingredient has been reviewed by sccs.
Is Diethylamino Hydroxybenzoyl Hexyl Benzoate allowed in the EU?
Diethylamino Hydroxybenzoyl Hexyl Benzoate EU regulatory status: permitted. Maximum allowed concentration: 10%. This is based on EU Regulation 1223/2009 and its amendments.
What does Diethylamino Hydroxybenzoyl Hexyl Benzoate do in cosmetics?
Diethylamino Hydroxybenzoyl Hexyl Benzoate functions as: Broad-spectrum UVA organic UV filter; photostable UVA absorber; supports water-resistance and critical wavelength maintenance after immersion. It is classified as a UV Filter / Sunscreen in our database. CAS number: 302776-68-7.
What is the Margin of Safety for Diethylamino Hydroxybenzoyl Hexyl Benzoate?
not established The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.
What is the NOAEL for Diethylamino Hydroxybenzoyl Hexyl Benzoate?
The NOAEL (No Observed Adverse Effect Level) for Diethylamino Hydroxybenzoyl Hexyl Benzoate is 200 mg/kg bw/day based on a Developmental study via oral route in rat. A total of 10 study endpoints are available. Source: COSMOS_DB.
Compliance Tools
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