Moderate Fragrance Sensitization Data Dermal Penetration

Benzyl Cinnamate

INCI: BENZYL CINNAMATE

CAS Number
None
Function
fragrance; fixative
Safety Rating
MODERATE

Regulatory Status

🇪🇺 EU Status restricted
EU Max Conc. Declarable EU allergen; labelling required >10 ppm leave-on / >100 ppm rinse-off
🇺🇸 US Status permitted
US Notes Permitted; RIFM-assessed; allergen declaration required for EU market

For full compliance data across 55 jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety (MoS)
not established
Dermal Absorption
moderate
Sensitization
moderate

Calculate MoS for your specific formulation with the MoS Calculator.

Sensitization Profile

Contact sensitization data for Benzyl Cinnamate based on clinical patch test studies and IFRA standards.

Sensitization Rate
low
Allergen Class
fragrance
EU Allergen Listed
yes
Patch Test Positive Rate
0.3%
Cross-reactivity Group
balsam-of-peru-group
Reaction Type
contact-dermatitis
IFRA Restricted

Source: ESSCA/IVDK

Dermal Penetration Profile

Skin absorption and penetration characteristics of Benzyl Cinnamate, relevant to systemic exposure and MoS calculations.

Absorption %
12-22%
Penetration Level
epidermis
Penetration Depth
epidermis
Molecular Weight
238.3 Da
Log P
4.6
Systemic Absorption
minimal
Topical Bioavailability
8-18%
Safety Margin Factor
moderate
Vehicle Dependent
Yes — absorption varies by formulation

Source: SCCS/1459/11, IFRA

Expert Verdict

EU declarable fragrance allergen with mandatory labelling above specified thresholds; commonly used as fragrance fixative with moderate sensitization profile.

⚠️
Concern Level: Moderate

Regulatory Flags

allergen-eu sensitization-risk eu-labelling-required original-26-allergen eu_children_restricted ifra_fragrance fda_food_additive eu_cosing_listed jecfa_safe

Frequently Asked Questions

Is Benzyl Cinnamate safe in cosmetics?

EU declarable fragrance allergen with mandatory labelling above specified thresholds; commonly used as fragrance fixative with moderate sensitization profile. The EU classifies Benzyl Cinnamate as "restricted". Safety rating: MODERATE.

Is Benzyl Cinnamate allowed in the EU?

Benzyl Cinnamate EU regulatory status: restricted. Maximum allowed concentration: Declarable EU allergen; labelling required >10 ppm leave-on / >100 ppm rinse-off. This is based on EU Regulation 1223/2009 and its amendments.

What does Benzyl Cinnamate do in cosmetics?

Benzyl Cinnamate functions as: fragrance; fixative. It is classified as a Fragrance in our database. CAS number: None.

What is the Margin of Safety for Benzyl Cinnamate?

not established The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.

Compliance Tools

Check Benzyl Cinnamate compliance across multiple jurisdictions:

🔬
Ingredient Decoder
Paste a full ingredient list for instant analysis
 🌸
82 Allergen Checker
Check for EU declarable fragrance allergens
 🧪
Substance Compliance
Check compliance across 55 jurisdictions
 🧮
MoS Calculator
Calculate Margin of Safety using SCCS methodology
 ⚗️
Heavy Metal Limits
Compare limits across jurisdictions

Related Ingredients

Isoeugenol
Poor
Cinnamyl Alcohol
Moderate
Chloroatranol
Poor
Iso E Super
Excellent
Lavender Oil (Lavandula Angustifolia Oil)
Good
Browse all 30,000+ ingredients →
📱

Is Benzyl Cinnamate in Your Products?

Scan any product label with Piro — our free ingredient scanner. Point your camera at the ingredients list and get instant safety scores for every ingredient.

Try Piro Free →

Analyze Your Full Ingredient List

Paste any INCI list into the Decoder for instant safety analysis, or calculate the Margin of Safety for Benzyl Cinnamate in your formulation.

Ingredient Decoder MoS Calculator