Is Camellia Sinensis Leaf Extract safe in cosmetics?
Camellia Sinensis Leaf Extract has a safety rating of "EXCELLENT" in our database. EU status: permitted. US status: permitted. 8 toxicological study endpoint(s) are available in our database.
Camellia Sinensis Leaf Extract
Also known as: Camellia sinensis extract, Camellia thea extract
INCI: CAMELLIA SINENSIS LEAF EXTRACT
Camellia Sinensis Leaf Extract (CAS 84650-60-2) is a cosmetic active ingredient functioning as Antioxidant, Skin conditioning, Anti-inflammatory. Reported NOAEL =100 mg/kg/d (CIR_vision_codex); EU Regulation 1223/2009 status: permitted. Industrial safety data is also available in the chemical safety database. Same-CAS public records also appear in pharmaceutical data.
View industrial chemical safety profile for CAS 84650-60-2 →
Auto-generated CPSR Part A draft with source citations
Function
Antioxidant, Skin conditioning, Anti-inflammatory
Safety Rating
EXCELLENT
Regulatory Status
EU EU Status
permitted
US US Status
permitted
US Notes
Cosmetic ingredient. No FDA concentration restrictions.
For full compliance data across multiple jurisdictions, use the Substance Compliance tool.
Safety Data
Margin of Safety, dermal absorption, and sensitization profile summaries for Camellia Sinensis Leaf Extract.
Calculate MoS for your specific formulation with the MoS Calculator.
Toxicological Studies
8 study endpoints found for Camellia Sinensis Leaf Extract. NOAEL (No Observed Adverse Effect Level) values are used to calculate the Margin of Safety per SCCS methodology.
| Endpoint | Value | Route | Species | Study Type | Source |
|---|---|---|---|---|---|
| NOAEL | =100 mg/kg/d | oral | - | oral toxicity | CIR_vision_codex |
| NOAEL | =100 mg/kg/d | oral | - | oral toxicity | CIR_vision_codex |
| NOAEL | =100 mg/kg/d | oral | - | oral toxicity | CIR_vision_codex |
| NOAEL | =100 mg/kg/d | oral | - | oral toxicity | CIR_vision_codex |
| NOAEL | =200 mg/kg body weight | oral | - | oral toxicity | CIR_vision_codex |
| NOAEL | =200 mg/kg body weight | oral | - | oral toxicity | CIR_vision_codex |
| NOAEL | =200 mg/kg body weight | oral | - | oral toxicity | CIR_vision_codex |
| NOAEL | =200 mg/kg body weight | oral | - | oral toxicity | CIR_vision_codex |
Typical Use Concentrations
Reported concentration ranges per product category from SCCS/CIR/industry sources.
| Product Category | Typical Range | Max Reported | Source |
|---|---|---|---|
| Face Cream | 0.01–2 | 2 | CIR (2014 report citing VCRP/PCPC) |
| Shampoo | 0.01–2 | 2 | CIR (2014 report citing VCRP) |
Additional Ingredient Properties
1 property record from structured ingredient metadata.
anti_aging
{"anti_aging_claim": "antioxidant-protection, anti-inflammatory, anti-wrinkle", "mechanism_of_action": "Green tea polyphenols, EGCG, catechins", "target_skin_layer": "epidermis", "collagen_stimulation": "No", "elastin_protection": "Mild", "wrinkle_reduction_pct": "8-15", "clinical_study_duration_weeks": "8", "sample_size": "30", "double_blind": "Yes", "placebo_controlled": "Yes", "published_journa…
Function Categories & List Membership
Cosmetic/Chemical Function Categories
Antioxidant
Astringent
Biocide
Bleaching agent
Deodorizer
Flavouring and nutrient
Fragrance
Humectant
Pharmaceutical
Softener and conditioner
Regulatory List Membership (3)
EU Regulated in Personal Care
EU Restricted for Children (Cosmetics)
FDA Substances Added to Food (EAFUS)
Expert Verdict
Expert safety assessment and concern-level summary for Camellia Sinensis Leaf Extract.
Regulatory Flags
rosacea-safe
antioxidant
anti-inflammatory
ros-scavenging
stability-sensitive
eu_children_restricted
fda_food_additive
NOAEL Studies Summary
View details ->Public NOAEL study rows linked to Camellia Sinensis Leaf Extract by CAS number or substance name.
Studies
8
Lowest NOAEL
100
Highest NOAEL
200
Units vary across source rows: mg/kg body weight, mg/kg/d
CIR_vision_codex
Known Synonyms
Camellia sinensis extract
Camellia thea extract
Chemical Function
Humectant
Softener and conditioner
Biocide
UV stabilizer
Antioxidant
Astringent
Deodorizer
Regulatory Lists
children; Europe; Personal care
children; Europe; Personal care - dental care - toothpaste
Europe; Personal care
Europe; Personal care
Europe; Personal care
food_additive; Substances Added to Food (formerly EAFUS) (2/2019)
Australian Status
AICIS status: listed
Cross-Vertical Safety Context
Same-CAS public records found in pharmaceutical data.
SOURCE
ChEMBL / DrugCentral / FAERS
DB_PHARMA CAS match
Pharmaceutical Data
Same-CAS rows from the pharmaceutical spoke database.
Compound
sinecatechins
ChEMBL ID
CHEMBL1201723
Frequently Asked Questions
Is Camellia Sinensis Leaf Extract allowed in the EU?
Camellia Sinensis Leaf Extract EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.
What does Camellia Sinensis Leaf Extract do in cosmetics?
Camellia Sinensis Leaf Extract functions as: Antioxidant, Skin conditioning, Anti-inflammatory. It is classified as a Active Ingredient in our database. CAS number: 84650-60-2.
What is the NOAEL for Camellia Sinensis Leaf Extract?
The NOAEL (No Observed Adverse Effect Level) for Camellia Sinensis Leaf Extract is =100 mg/kg/d based on a oral toxicity study via oral route in rat. A total of 8 study endpoints are available. Source: CIR_vision_codex.
Is Camellia Sinensis Leaf Extract used outside cosmetics?
Camellia Sinensis Leaf Extract also appears in pharmaceutical data. The cross-vertical cards on this page render same-CAS public rows from the matched databases.
Compliance Tools
Check Camellia Sinensis Leaf Extract compliance across multiple jurisdictions:
Ingredient Decoder
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82 Allergen Checker
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Substance Compliance
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MoS Calculator
Calculate Margin of Safety using SCCS methodology
Heavy Metal Limits
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