Is Cocamide DEA safe in cosmetics?
Cocamide DEA has a safety rating of "GOOD" in our database. EU status: restricted. US status: permitted. 1 toxicological study endpoint(s) are available in our database.
Cocamide DEA
Also known as: Coconut oil acid diethanolamine condensate, Mapon MM, Alkanolamide of coconut oil fatty acids and diethanolamine, Amides, coco, N,N-bis(2-hydroxyethyl), N,N-Bis(hydroxyethyl) coco amide (+14 more)
INCI: COCAMIDE DEA
Cocamide DEA (CAS 68603-42-9) is a cosmetic uv filter / sunscreen functioning as UV filter. Reported NOAEL =1000 mg/kg bw/day in Rat (ToxValDB_ECHA_IUCLID); EU Regulation 1223/2009 status: restricted, max 2%. Industrial safety data is also available in the chemical safety database.
View industrial chemical safety profile for CAS 68603-42-9 →
Auto-generated CPSR Part A draft with source citations
Function
UV filter
Safety Rating
GOOD
Regulatory Status
EU EU Status
restricted
EU Max Conc.
2%
US US Status
permitted
US Notes
CIR: SQ - IJT 32(Suppl. 1):36-58, 2013
For full compliance data across multiple jurisdictions, use the Substance Compliance tool.
Safety Data
Margin of Safety, dermal absorption, and sensitization profile summaries for Cocamide DEA.
Calculate MoS for your specific formulation with the MoS Calculator.
Toxicological Studies
1 study endpoint found for Cocamide DEA. NOAEL (No Observed Adverse Effect Level) values are used to calculate the Margin of Safety per SCCS methodology.
| Endpoint | Value | Route | Species | Study Type | Source |
|---|---|---|---|---|---|
| NOAEL | =1000 mg/kg bw/day | oral | Rat | developmental | ToxValDB_ECHA_IUCLID |
Sensitization Profile
Contact sensitization data for Cocamide DEA based on clinical patch test studies and IFRA standards.
Sensitization Rate
moderate
Allergen Class
surfactant
EU Allergen Listed
no
Patch Test Positive Rate
1.5%
Cross-reactivity Group
amidoamine-group
Reaction Type
contact-dermatitis
Source: NACDG; IVDK; ESSCA
IARC Carcinogenicity
International Agency for Research on Cancer (WHO) monograph evaluation.
IARC Group
2B
Volume
101
Evaluation Year
2011
Endocrine Disruptor Evidence (Expanded)
Cross-referenced EDC classifications, mechanism data, and dose-response evidence from EDLists, SIN List, and cosmetic-specific detail sources.
Cosmetic-Specific Mechanism
Category: surfactant
Receptor targets: ERα (indirect, via DEA)
LOEC: 100 µM
EU status: restricted (CMR 2A; banned from leave-on)
indirect modulator
Typical Use Concentrations
Reported concentration ranges per product category from SCCS/CIR/industry sources.
| Product Category | Typical Range | Max Reported | Source |
|---|---|---|---|
| Shampoo | 1–3 | 5 | CIR/VCRP |
Additional Ingredient Properties
8 property records from structured ingredient metadata.
allergen_detail
{"eu_allergen_listed": "no", "allergen_class": "surfactant", "cross_reactivity_group": "amidoamine-group", "patch_test_frequency_pct": "1.5", "sensitization_rate": "moderate", "common_reaction_type": "contact-dermatitis", "ifra_restricted": "no", "source": "NACDG; IVDK; ESSCA"}
baby_pediatric
{"cas_number": "CAS-83847", "ingredient_class": "cleanser_baby", "pediatric_safety_rating": "good", "minimum_age_months": "3", "neonatal_safe": "no", "premature_infant_safe": "insufficient_data", "skin_barrier_maturity_consideration": "Mild derivative surfactant", "transepidermal_absorption_risk_pediatric": "low", "systemic_exposure_concern_pediatric": "low", "dose_per_kg_body_weight_concern": "Su…
concentration
{"min_concentration_pct": "1.0", "max_concentration_pct": "5.0", "typical_concentration_pct": "3.0", "product_type": "Shampoo", "function_at_concentration": "Foam booster, viscosity builder", "source": "CIR Safety Assessment"}
ecotoxicity
{"biodegradable": "partial", "biodegradation_days": "90-180", "bioaccumulative": "yes", "aquatic_toxicity_level": "moderate", "coral_reef_safe": "unknown", "marine_toxicity": "moderate toxicity", "freshwater_toxicity": "bioaccumulative potential", "endocrine_disruptor": "suspected", "persistent_organic_pollutant": "no", "microplastic": "no", "nano_particle": "no", "hawaii_banned": "no", "eu_restri…
ph_stability
{"optimal_ph_min": "5.0", "optimal_ph_max": "9.0", "stable_ph_min": "4.0", "stable_ph_max": "10.0", "degrades_above_ph": "11.0", "degrades_below_ph": "3.5", "ph_dependent_function": "Non-ionic; viscosity builder", "formulation_note": "Restricted in some regions", "source": "Formulation literature"}
sensory
{"silky": "medium", "smooth, glides easily": "rich, thick foam", "dry-touch, non-greasy": "clean, soft", "instant": "moderate", "none": "very-high", "low": "high", "w/o": "o/w", "very-high": "moderate", "no": "no", "yes": "no", "1.40": "1.47", "transparent": "translucent", "colorless": "amber", "excellent": "good", "light": "medium", "synthetic": "botanical"}
skin_suitability
{"oily_skin": "avoid", "dry_skin": "avoid", "sensitive_skin": "avoid", "combination_skin": "avoid", "normal_skin": "avoid", "acne_prone": "avoid", "rosacea": "avoid", "eczema": "avoid", "hyperpigmentation": "avoid", "aging_mature": "avoid", "dehydrated": "avoid", "skin_benefit_primary": "surfactant", "skin_benefit_secondary": "foam-booster", "mechanism_of_action": "Diethanolamine compound, carcino…
surfactant
{"cas_number": "49120-70-0", "surfactant_type": "nonionic", "chemical_class": "fatty_acid_soap", "charge_at_use_ph": "neutral", "cmc_critical_micelle_concentration_mm": "0.022281837502994478", "hlb_value": "15.2979336736923", "foam_volume_ml_ross_miles": "89", "foam_quality": "minimal", "foam_stability_5min_pct": "79", "cleansing_power_rating_1_to_10": "3.406121318811288", "oil_emulsification_capa…
Function Categories & List Membership
Cosmetic/Chemical Function Categories
Corrosion inhibitor
Dispersing agent
Emulsifier
Foamant
Processing aids not otherwise specified
Surfactant (surface active agent)
Thickening agent
Viscosity modifier
Wetting agent (non-aqueous)
Regulatory List Membership (3)
EU Regulated in Personal Care
EU Restricted for Children (Cosmetics)
FDA Substances Added to Food (EAFUS)
Expert Verdict
Expert safety assessment and concern-level summary for Cocamide DEA.
Regulatory Flags
EU Restricted
eu_children_restricted
fda_food_additive
NOAEL Studies Summary
View details ->Public NOAEL study rows linked to Cocamide DEA by CAS number or substance name.
Studies
1
Lowest NOAEL
1000 mg/kg bw/day
Highest NOAEL
1000 mg/kg bw/day
ToxValDB_ECHA_IUCLID
Known Synonyms
Coconut oil acid diethanolamine condensate
Mapon MM
Alkanolamide of coconut oil fatty acids and diethanolamine
Amides, coco, N,N-bis(2-hydroxyethyl)
N,N-Bis(hydroxyethyl) coco amide
Clindrol 202CGN
Coconut fatty acid diethanolamine condensate
Coconut oil acid diethanolamine (con 2/1)
Diethanolamine, coconut fatty acids condensate
EINECS 271-657-0
NCI-C55312
Amides, N,N-bis(hydroxyethyl) coco
Conco Emulsifier K
N,N-Bis(hydroxyethyl coco amides
Naxonol RN 66
Cocamides diethanolamines
Marlamid DF 1218
Amide 6501
Cola Cor 600
Chemical Function
Surfactant (surface active agent)
Emulsifier
Viscosity modifier
Regulatory Lists
food_additive; Substances Added to Food (formerly EAFUS) (2/2019)
inert_ingredient; non_food_use; Pesticides
active_ingredient; Europe; Pesticides
Europe; Personal care - body hygiene - hand soap
children; Europe; Personal care
children; Europe; Personal care - specialized bath products - bath salts
children; Europe; Personal care - body hygiene - body wash
children; Europe; Personal care - hair styling and care - shampoo
children; Europe; Personal care - specialized bath products - bubble bath
children; Europe; Personal care
Europe; Personal care - hair styling and care - shampoo-dandruff
Europe; Personal care - hair styling and care - shampoo-dandruff
Europe; Personal care
Europe; Personal care
Cleaning products and household care; Europe
active_ingredient; Pesticides
active_ingredient; Pesticides
active_ingredient; Pesticides
Australian Status
AICIS status: listed
Frequently Asked Questions
Is Cocamide DEA allowed in the EU?
Cocamide DEA EU regulatory status: restricted. Maximum allowed concentration: 2%. This is based on EU Regulation 1223/2009 and its amendments.
What does Cocamide DEA do in cosmetics?
Cocamide DEA functions as: UV filter. It is classified as a UV Filter / Sunscreen in our database. CAS number: 68603-42-9.
What is the NOAEL for Cocamide DEA?
The NOAEL (No Observed Adverse Effect Level) for Cocamide DEA is =1000 mg/kg bw/day based on a developmental study via oral route in Rat. Source: ToxValDB_ECHA_IUCLID.
Compliance Tools
Check Cocamide DEA compliance across multiple jurisdictions:
Ingredient Decoder
Paste a full ingredient list for instant analysis
82 Allergen Checker
Check for EU declarable fragrance allergens
Substance Compliance
Check compliance across multiple jurisdictions
MoS Calculator
Calculate Margin of Safety using SCCS methodology
Heavy Metal Limits
Compare limits across jurisdictions
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