Regulatory Status
For full compliance data across 55 jurisdictions, use the Substance Compliance tool.
Safety Data
Calculate MoS for your specific formulation with the MoS Calculator.
Toxicological Studies
1 study endpoint found for Dibromocyanoacetamide (DBNPA). NOAEL (No Observed Adverse Effect Level) values are used to calculate the Margin of Safety per SCCS methodology.
| Endpoint | Value | Route | Species | Study Type | Source |
|---|---|---|---|---|---|
| NOAEL | 58.5 mg/kg bw/day | oral | rat | Subchronic | COSMOS_DB |
Expert Verdict
Regulatory red flag: absent from EU Annex V; GHS H317 (skin sensitizer), H314 (corrosive), H400/H410 (aquatic toxicity); rapidly degrades but releases cyanide and bromide ions; candidate for substitution under BPR; do NOT formulate into cosmetics
Regulatory Flags
Frequently Asked Questions
Is Dibromocyanoacetamide (DBNPA) safe in cosmetics?
Regulatory red flag: absent from EU Annex V; GHS H317 (skin sensitizer), H314 (corrosive), H400/H410 (aquatic toxicity); rapidly degrades but releases cyanide and bromide ions; candidate for substitution under BPR; do NOT formulate into cosmetics The EU classifies Dibromocyanoacetamide (DBNPA) as "permitted". Safety rating: POOR. 1 toxicological study endpoint(s) are available in our database.
Is Dibromocyanoacetamide (DBNPA) allowed in the EU?
Dibromocyanoacetamide (DBNPA) EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.
What does Dibromocyanoacetamide (DBNPA) do in cosmetics?
Dibromocyanoacetamide (DBNPA) functions as: Antimicrobial / biocide (industrial preservative). It is classified as a cosmetic ingredient in our database. CAS number: 10222-01-2.
What is the Margin of Safety for Dibromocyanoacetamide (DBNPA)?
not established The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.
What is the NOAEL for Dibromocyanoacetamide (DBNPA)?
The NOAEL (No Observed Adverse Effect Level) for Dibromocyanoacetamide (DBNPA) is 58.5 mg/kg bw/day based on a Subchronic study via oral route in rat. Source: COSMOS_DB.
Compliance Tools
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Related Ingredients
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