Excellent Emollient NOAEL Data

Dicaprylyl Carbonate

Also known as: Dioctyl carbonate, UNII-609A3V1SUA, Cetiol CC, Cetiol DD, EC 434-850-2

INCI: DICAPRYLYL CARBONATE

Dicaprylyl Carbonate (CAS 1680-31-5) is a cosmetic emollient functioning as Emollient, Solvent. Reported NOAEL =1000 mg/kg bw/day in Rat (ToxValDB_ECHA_IUCLID); EU Regulation 1223/2009 status: permitted. Industrial safety data is also available in the chemical safety database. Same-CAS public records also appear in industrial chemical safety data.

View industrial chemical safety profile for CAS 1680-31-5 →

Auto-generated CPSR Part A draft with source citations
Function
Emollient, Solvent
Safety Rating
EXCELLENT

Chemistry & Identifiers

Formula
C17H34O3
MW
286.4 g/mol
EC Number
434-850-2
PubChem CID
9904000
IUPAC Name
dioctyl carbonate
InChIKey
PKPOVTYZGGYDIJ-UHFFFAOYSA-N

Regulatory Status

EU EU Status permitted
US US Status permitted
US Notes Not restricted

For full compliance data across multiple jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety, dermal absorption, and sensitization profile summaries for Dicaprylyl Carbonate.

Calculate MoS for your specific formulation with the MoS Calculator.

Toxicological Studies

1 study endpoint found for Dicaprylyl Carbonate. NOAEL (No Observed Adverse Effect Level) values are used to calculate the Margin of Safety per SCCS methodology.

Endpoint Value Route Species Study Type Source
NOAEL =1000 mg/kg bw/day oral Rat subchronic ToxValDB_ECHA_IUCLID

ECHA REACH Registration

European Chemicals Agency REACH dossier and Substances of Very High Concern listing.

Registration Type
Full
Tonnage Band
1,000 - 10,000 tonnes
Substance Type
SUBSTANCE
SVHC Candidate
No

Additional Ingredient Properties

7 property records from structured ingredient metadata.

concentration
{"min_concentration_pct": "2.0", "max_concentration_pct": "15.0", "typical_concentration_pct": "8.0", "product_type": "Sunscreen", "function_at_concentration": "Emollient", "source": "CIR Safety Assessment"}
cost_pricing
{"cost_tier": "mid-range", "estimated_cost_per_kg_usd_low": "16", "estimated_cost_per_kg_usd_high": "30", "natural_premium_markup_pct": "0", "organic_certified_premium_pct": "0", "supply_chain_volatility": "low", "primary_source_region": "Europe", "bulk_discount_threshold_kg": "200", "seasonal_price_variation": "low", "commodity_or_specialty": "specialty", "substitute_ingredients": "Dicaprylyl Eth…
ecotoxicity
{"biodegradable": "yes", "biodegradation_days": "28-60", "bioaccumulative": "no", "aquatic_toxicity_level": "low", "coral_reef_safe": "yes", "marine_toxicity": "low aquatic toxicity", "freshwater_toxicity": "minimal impact", "endocrine_disruptor": "no", "persistent_organic_pollutant": "no", "microplastic": "no", "nano_particle": "no", "hawaii_banned": "no", "eu_restricted_environmental": "no", "pa…
emulsion_hlb
{"hlb_required_as_emulsifier": "no", "hlb_required_of_oil_phase": "11", "co_emulsifier_pairs": "polysorbate_80,ceteth_20", "optimal_oil_phase_pct": "10-30", "optimal_water_phase_pct": "70-90", "droplet_size_range_um": "1-20", "creaming_resistance": "good", "coalescence_resistance": "good", "ostwald_ripening_resistance": "moderate", "freeze_thaw_stability": "moderate", "rheology_modifier_type": "ne…
ph_stability
{"optimal_ph_min": "3.0", "optimal_ph_max": "10.0", "stable_ph_min": "3.0", "stable_ph_max": "11.0", "ph_dependent_function": "Dry-feel emollient", "formulation_note": "Excellent stability", "source": "Formulation literature"}
sensory
{"silky": "light", "smooth, glides easily": "silky, elegant", "dry-touch, non-greasy": "dry, powdery", "instant": "fast", "low": "low", "w/o": "o/w", "very-high": "excellent", "no": "no", "yes": "no", "1.40": "1.42", "transparent": "transparent", "colorless": "colorless", "excellent": "excellent", "light": "light", "synthetic": "synthetic"}
solubility_hlb
{"water_soluble": "no", "oil_soluble": "yes", "hlb_required": "5.0", "soluble_in": "oils, ethanol, silicones", "insoluble_in": "water, glycerin, propylene glycol", "log_p": "5.1", "appearance": "clear liquid", "source": "BASF"}

Function Categories & List Membership

Cosmetic/Chemical Function Categories
Softener and conditioner
Regulatory List Membership (2)
EU Regulated in Personal Care EU Restricted for Children (Cosmetics)

Expert Verdict

Expert safety assessment and concern-level summary for Dicaprylyl Carbonate.

Regulatory Flags

eu_children_restricted

NOAEL Studies Summary

View details ->

Public NOAEL study rows linked to Dicaprylyl Carbonate by CAS number or substance name.

Studies
1
Lowest NOAEL
1000 mg/kg bw/day
Highest NOAEL
1000 mg/kg bw/day
ToxValDB_ECHA_IUCLID

Known Synonyms

Dioctyl carbonate UNII-609A3V1SUA Cetiol CC Cetiol DD EC 434-850-2

Chemical Function

Softener and conditioner

Regulatory Lists

children; Europe; Personal care children; Europe; Personal care Europe; Personal care Europe; Personal care Europe; Personal care Canada; Personal care; Substances in PCP - Canada (4/2014)

Australian Status

AICIS status: listed_with_terms

Specific information requirements: Obligations to provide information apply. You must tell us within 28 days if the circumstances of your importation or manufacture (introduction) are different to those in our assessment.

Frequently Asked Questions

Is Dicaprylyl Carbonate safe in cosmetics?

Dicaprylyl Carbonate has a safety rating of "EXCELLENT" in our database. EU status: permitted. US status: permitted. 1 toxicological study endpoint(s) are available in our database.

Is Dicaprylyl Carbonate allowed in the EU?

Dicaprylyl Carbonate EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.

What does Dicaprylyl Carbonate do in cosmetics?

Dicaprylyl Carbonate functions as: Emollient, Solvent. It is classified as a Emollient in our database. CAS number: 1680-31-5.

What is the NOAEL for Dicaprylyl Carbonate?

The NOAEL (No Observed Adverse Effect Level) for Dicaprylyl Carbonate is =1000 mg/kg bw/day based on a subchronic study via oral route in Rat. Source: ToxValDB_ECHA_IUCLID.

Is Dicaprylyl Carbonate used outside cosmetics?

Dicaprylyl Carbonate also appears in industrial chemical safety data. The cross-vertical cards on this page render same-CAS public rows from the matched databases.

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