Iodoform

INCI: IODOFORM

CAS Number
75-47-8
Function
Antimicrobial agent; functional fragrance
Safety Rating
POOR

Regulatory Status

๐Ÿ‡ช๐Ÿ‡บ EU Status prohibited
๐Ÿ‡บ๐Ÿ‡ธ US Status restricted
US Notes Permitted โ€” not specifically restricted under 21 CFR Parts 700โ€“740. Subject to general safety requirement under FD&C Act ยง601

For full compliance data across 55 jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety (MoS)
not established
Dermal Absorption
moderate
Sensitization
high

Calculate MoS for your specific formulation with the MoS Calculator.

Expert Verdict

Iodine liberation may disrupt thyroid function at systemic doses; historical toxicity reports including CNS depression and hepatotoxicity; strong characteristic odor limits practical use; no published MoS calculation for dermal cosmetic exposure.

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Concern Level: High

Regulatory Flags

fragrance-component ifra_fragrance

Frequently Asked Questions

Is Iodoform safe in cosmetics?

Iodine liberation may disrupt thyroid function at systemic doses; historical toxicity reports including CNS depression and hepatotoxicity; strong characteristic odor limits practical use; no published MoS calculation for dermal cosmetic exposure. The EU classifies Iodoform as "prohibited". Safety rating: POOR.

Is Iodoform allowed in the EU?

Iodoform EU regulatory status: prohibited. This is based on EU Regulation 1223/2009 and its amendments.

What does Iodoform do in cosmetics?

Iodoform functions as: Antimicrobial agent; functional fragrance. It is classified as a cosmetic ingredient in our database. CAS number: 75-47-8.

What is the Margin of Safety for Iodoform?

not established The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.

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