Is Iodoform safe in cosmetics?
Iodoform has a safety rating of "POOR" in our database. EU status: prohibited. US status: restricted.
Poor
Cosmetic Ingredient
Iodoform
Also known as: EINECS 200-874-5, NCI-C04568, Trijodmethane, UNII-KXI2J76489
INCI: IODOFORM
Iodoform (CAS 75-47-8) is a cosmetic cosmetic ingredient functioning as Antimicrobial agent; functional fragrance. EU Regulation 1223/2009 status: prohibited. Industrial safety data is also available in the chemical safety database. Same-CAS public records also appear in industrial chemical safety data.
View industrial chemical safety profile for CAS 75-47-8 →
Auto-generated CPSR Part A draft with source citations
Cross-Vertical Regulatory Divergence
Iodoform is prohibited in EU cosmetics but has active industrial GHS classifications (H302, H312, H319, H332, H336, H411, H315, H401).
Source: Cosmetics: ingredients.eu status; Chemicals: ghs classifications.signal word/hazard statement code
Function
Antimicrobial agent; functional fragrance
Safety Rating
POOR
Chemistry & Identifiers
IUPAC Name
iodoform
InChIKey
OKJPEAGHQZHRQV-UHFFFAOYSA-N
Regulatory Status
EU EU Status
prohibited
US US Status
restricted
US Notes
Permitted — not specifically restricted under 21 CFR Parts 700–740. Subject to general safety requirement under FD&C Act §601
For full compliance data across multiple jurisdictions, use the Substance Compliance tool.
Safety Data
Margin of Safety, dermal absorption, and sensitization profile summaries for Iodoform.
Calculate MoS for your specific formulation with the MoS Calculator.
PubChem Annotations
Safety and regulatory annotations from PubChem (NCBI) aggregated sources.
Safety (1)
Carcinogen Classification
Iodoform | TR-110: Bioassay of Iodoform for Possible Carcinogenicity (CASRN 75-47-8) (1978 ) | 04/26/78 | No Evidence | No Evidence | No Evidence | No Evidence | Under the conditions of this bioassay, no convincing evidence was provided for the carcinogenicity of iodoform in Osborne-Mendel rats or B6C3F1 mice.
Source: NTP Technical Reports
Function Categories & List Membership
Cosmetic/Chemical Function Categories
Biocide
Fragrance
Regulatory List Membership (2)
IFRA Fragrance Transparency List
FDA Indirect Food Contact Additives
Expert Verdict
Expert safety assessment and concern-level summary for Iodoform.
Regulatory Flags
fragrance-component
ifra_fragrance
Known Synonyms
EINECS 200-874-5
NCI-C04568
Trijodmethane
UNII-KXI2J76489
Chemical Function
Biocide
Fragrance
Regulatory Lists
Indirect additives food contact (10/2018)
Canada; pharmaceutical
Canada; pharmaceutical
active_ingredient; Europe; Pesticides
IFRA Transparency
Frequently Asked Questions
Is Iodoform allowed in the EU?
Iodoform EU regulatory status: prohibited. This is based on EU Regulation 1223/2009 and its amendments.
What does Iodoform do in cosmetics?
Iodoform functions as: Antimicrobial agent; functional fragrance. It is classified as a cosmetic ingredient in our database. CAS number: 75-47-8.
Is Iodoform used outside cosmetics?
Iodoform also appears in industrial chemical safety data. The cross-vertical cards on this page render same-CAS public rows from the matched databases.
Does Iodoform have different safety status in cosmetics vs industrial chemicals?
Iodoform is prohibited in EU cosmetics but has active industrial GHS classifications (H302, H312, H319, H332, H336, H411, H315, H401).
Compliance Tools
Check Iodoform compliance across multiple jurisdictions:
Ingredient Decoder
Paste a full ingredient list for instant analysis
82 Allergen Checker
Check for EU declarable fragrance allergens
Substance Compliance
Check compliance across multiple jurisdictions
MoS Calculator
Calculate Margin of Safety using SCCS methodology
Heavy Metal Limits
Compare limits across jurisdictions
Related Ingredients
2,6-Dimethyl-7-octen-2-ol (Dihydromyrcenol)
Excellent
Same category
Fragrance (perfuming), masking
2-Ethoxy-2,6,6-Trimethyl-9-Methylenebicyclo[3.3.1]Nonane (Boisiris™)
Excellent
Same category
Fragrance (rich woody, orris/iris roo...
3,6-Dimethyl-3-Octyl Acetate
Excellent
Same category
Fragrance / Perfuming agent with flor...
3-Methyl-5-(2,2,3-Trimethyl-3-Cyclopentenyl)Pent-4-En-2-Ol (Sandalore)
Excellent
Same category
Perfuming / Fragrance (sandalwood note)
4-Tert-Butylcyclohexyl Acetate
Excellent
Same category
Fragrance
Acetoin
Excellent
Same category
Skin conditioning, fragrance
1,2,4-Benzenetriacetate
Poor
Similar safety
Hair dye precursor (triacetyl ester o...
1,2,4-Trihydroxybenzene
Poor
Similar safety
Hair colorant (auto-oxidative dye)
1,3-Bis-(Isocyanatomethyl) Cyclohexane
Poor
Similar safety
Monomer / cross-linking agent used in...
1,4-Butanediol
Poor
Similar safety
Solvent, humectant, viscosity control...
1,6-Hexamethylene Diisocyanate (HDI)
Poor
Similar safety
Monomer and crosslinker in polymer sy...
1,6-Hexanediamine
Poor
Similar safety
Industrial chemical (nylon monomer); ...
ACETALDEHYDE
Moderate
Chemical family
Fragrance
Chlorofluorocarbons (CFCs)
Poor
Chemical family
aerosol propellants
DICHLOROMETHANE
Moderate
Chemical family
Perfuming, Solvent
Is Iodoform in Your Products?
Scan any product label with Piro — our free ingredient scanner. Point your camera at the ingredients list and get instant safety scores for every ingredient.
Try Piro Free →Analyze Your Full Ingredient List
Paste any INCI list into the Decoder for instant safety analysis, or calculate the Margin of Safety for Iodoform in your formulation.