Regulatory Status
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Safety Data
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Expert Verdict
Konjac glucomannan hydrolysate is an emerging prebiotic active with a specific anti-acne mechanism: when combined with Lactobacillus commensals in synbiotic formulations, it significantly inhibits C. acnes growth through selective amplification of competitive exclusion. The hydrolysate form (lower MW) is the prebiotic-active species, while intact high-MW glucomannan primarily acts as film former/thickener. Excellent safety profile with a long history of food and cosmetic use. Most regulatory-friendly microbiome category as it contains no live organisms. Best combined with alpha-glucan oligosaccharide, FOS, and Lactobacillus Ferment in acne-prone synbiotic systems.
Regulatory Flags
Frequently Asked Questions
Is Konjac Glucomannan safe in cosmetics?
Konjac glucomannan hydrolysate is an emerging prebiotic active with a specific anti-acne mechanism: when combined with Lactobacillus commensals in synbiotic formulations, it significantly inhibits C. acnes growth through selective amplification of competitive exclusion. The hydrolysate form (lower MW) is the prebiotic-active species, while intact high-MW glucomannan primarily acts as film former/thickener. Excellent safety profile with a long history of food and cosmetic use. Most regulatory-friendly microbiome category as it contains no live organisms. Best combined with alpha-glucan oligosaccharide, FOS, and Lactobacillus Ferment in acne-prone synbiotic systems. The EU classifies Konjac Glucomannan as "permitted". Safety rating: EXCELLENT.
Is Konjac Glucomannan allowed in the EU?
Konjac Glucomannan EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.
What does Konjac Glucomannan do in cosmetics?
Konjac Glucomannan functions as: Prebiotic, C. acnes Inhibition (synbiotic), Microbiome Support, Film Former, Skin Conditioning, Humectant. It is classified as a Active Ingredient in our database. CAS number: 37220-17-0.
What is the Margin of Safety for Konjac Glucomannan?
adequate The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.
Compliance Tools
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