Regulatory Status
For full compliance data across 55 jurisdictions, use the Substance Compliance tool.
Safety Data
Calculate MoS for your specific formulation with the MoS Calculator.
Toxicological Studies
1 study endpoint found for Mannose. NOAEL (No Observed Adverse Effect Level) values are used to calculate the Margin of Safety per SCCS methodology.
| Endpoint | Value | Route | Species | Study Type | Source |
|---|---|---|---|---|---|
| NOAEL | 20 other | oral | mouse | oral | REACH |
Expert Verdict
Mannose is a simple monosaccharide humectant with excellent safety profile. CIR Panel found it safe as used in cosmetics with no EU restrictions and negative genotoxicity data.
Frequently Asked Questions
Is Mannose safe in cosmetics?
Mannose is a simple monosaccharide humectant with excellent safety profile. CIR Panel found it safe as used in cosmetics with no EU restrictions and negative genotoxicity data. The EU classifies Mannose as "permitted". Safety rating: EXCELLENT. 1 toxicological study endpoint(s) are available in our database.
Is Mannose allowed in the EU?
Mannose EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.
What does Mannose do in cosmetics?
Mannose functions as: Humectant, Skin Conditioning, Anti-Inflammatory. It is classified as a Cosmetic Ingredient in our database. CAS number: 3458-28-4.
What is the Margin of Safety for Mannose?
not established The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.
What is the NOAEL for Mannose?
The NOAEL (No Observed Adverse Effect Level) for Mannose is 20 other based on a oral study via oral route in mouse. Source: REACH.
Compliance Tools
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Related Ingredients
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