siRNA Technology

INCI: SIRNA

CAS Number
63231-63-0
Function
Gene expression modulator; post-transcriptional gene silencer
Safety Rating
POOR

Regulatory Status

๐Ÿ‡ช๐Ÿ‡บ EU Status prohibited
๐Ÿ‡บ๐Ÿ‡ธ US Status restricted
US Notes CIR review; no established Margin of Safety for cosmetic use

For full compliance data across 55 jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety (MoS)
not established
Dermal Absorption
moderate
Sensitization
low

Calculate MoS for your specific formulation with the MoS Calculator.

Expert Verdict

siRNA Technology is prohibited in EU cosmetics due to lack of established safety and Margin of Safety for cosmetic use.

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Concern Level: High

Regulatory Flags

EU Restricted

Frequently Asked Questions

Is siRNA Technology safe in cosmetics?

siRNA Technology is prohibited in EU cosmetics due to lack of established safety and Margin of Safety for cosmetic use. The EU classifies siRNA Technology as "prohibited". Safety rating: POOR.

Is siRNA Technology allowed in the EU?

siRNA Technology EU regulatory status: prohibited. This is based on EU Regulation 1223/2009 and its amendments.

What does siRNA Technology do in cosmetics?

siRNA Technology functions as: Gene expression modulator; post-transcriptional gene silencer. It is classified as a Cosmetic Ingredient in our database. CAS number: 63231-63-0.

What is the Margin of Safety for siRNA Technology?

not established The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.

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