Excellent Active Ingredient

Sodium Ascorbyl Phosphate

INCI: SODIUM ASCORBYL PHOSPHATE

CAS Number
66170-10-3
Function
Stable water-soluble vitamin C derivative; antioxidant; moderate tyrosinase inhibition; brightening activity via ascorbic acid release and free radical quenching
Safety Rating
EXCELLENT

Regulatory Status

๐Ÿ‡ช๐Ÿ‡บ EU Status permitted
๐Ÿ‡บ๐Ÿ‡ธ US Status permitted
US Notes No FDA restriction. Widely used in antioxidant and brightening formulations without concentration limit.

For full compliance data across 55 jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety (MoS)
adequate
Dermal Absorption
moderate
Sensitization
none

Calculate MoS for your specific formulation with the MoS Calculator.

Expert Verdict

Water-soluble, stable vitamin C derivative with antioxidant and brightening activity. Hydrolysed to endogenous ascorbic acid with excellent safety profile. Tyrosinase inhibition is moderate compared to MAP or ascorbyl glucoside. Primary value is antioxidant protection and as a brightening complement in multi-active formulations. Useful supporting brightening ingredient rather than a primary active; combine with stronger actives for meaningful clinical impact.

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Concern Level: None

Regulatory Flags

vitamin-c-derivative antioxidant brightening stable water-soluble moderate-tyrosinase-inhibition not-quasi-drug-japan hyperpigmentation

Frequently Asked Questions

Is Sodium Ascorbyl Phosphate safe in cosmetics?

Water-soluble, stable vitamin C derivative with antioxidant and brightening activity. Hydrolysed to endogenous ascorbic acid with excellent safety profile. Tyrosinase inhibition is moderate compared to MAP or ascorbyl glucoside. Primary value is antioxidant protection and as a brightening complement in multi-active formulations. Useful supporting brightening ingredient rather than a primary active; combine with stronger actives for meaningful clinical impact. The EU classifies Sodium Ascorbyl Phosphate as "permitted". Safety rating: EXCELLENT.

Is Sodium Ascorbyl Phosphate allowed in the EU?

Sodium Ascorbyl Phosphate EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.

What does Sodium Ascorbyl Phosphate do in cosmetics?

Sodium Ascorbyl Phosphate functions as: Stable water-soluble vitamin C derivative; antioxidant; moderate tyrosinase inhibition; brightening activity via ascorbic acid release and free radical quenching. It is classified as a Active Ingredient in our database. CAS number: 66170-10-3.

What is the Margin of Safety for Sodium Ascorbyl Phosphate?

adequate The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.

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