Regulatory Status
For full compliance data across 55 jurisdictions, use the Substance Compliance tool.
Safety Data
Calculate MoS for your specific formulation with the MoS Calculator.
Toxicological Studies
6 study endpoints found for Sodium Iodide. NOAEL (No Observed Adverse Effect Level) values are used to calculate the Margin of Safety per SCCS methodology.
| Endpoint | Value | Route | Species | Study Type | Source |
|---|---|---|---|---|---|
| NOAEL | 0.5 ppm | oral | rat | oral | REACH |
| NOAEL | 0.01 mg/kg bw/day | oral | code:3544 | oral | REACH |
| LOAEL | 70 mg/kg bw/day | oral | rat | oral | REACH |
| LOAEL | 100 mg/L drinking water | oral | rat | oral | REACH |
| LOAEL | 0.5 other | oral | rat | oral | REACH |
| LOAEL | 500 other | oral | rat | oral | REACH |
GHS Hazard Classification
Globally Harmonized System classification per ECHA C&L inventory and ILO/WHO International Chemical Safety Cards.
Expert Verdict
Reproductive toxicant (H360); thyroid damage through prolonged/repeated oral exposure; GHS Danger classification; not recommended for cosmetic use
Frequently Asked Questions
Is Sodium Iodide safe in cosmetics?
Reproductive toxicant (H360); thyroid damage through prolonged/repeated oral exposure; GHS Danger classification; not recommended for cosmetic use The EU classifies Sodium Iodide as "permitted". Safety rating: POOR. 6 toxicological study endpoint(s) are available in our database.
Is Sodium Iodide allowed in the EU?
Sodium Iodide EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.
What does Sodium Iodide do in cosmetics?
Sodium Iodide functions as: Skin conditioning agent; antimicrobial (limited cosmetic use). It is classified as a cosmetic ingredient in our database. CAS number: 7681-82-5.
What is the Margin of Safety for Sodium Iodide?
adequate The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.
What is the NOAEL for Sodium Iodide?
The NOAEL (No Observed Adverse Effect Level) for Sodium Iodide is 0.5 ppm based on a oral study via oral route in rat. A total of 6 study endpoints are available. Source: REACH.
Compliance Tools
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Related Ingredients
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