Regulatory Status
For full compliance data across 55 jurisdictions, use the Substance Compliance tool.
Safety Data
Calculate MoS for your specific formulation with the MoS Calculator.
Expert Verdict
Thymoquinone carries severe sensitization risk with documented case reports of SJS/TEN-mimicking reactions and confirmed allergenicity. No SCCS opinion or CIR monograph available; safety assessment burden falls entirely on individual assessor.
Regulatory Flags
Frequently Asked Questions
Is Thymoquinone safe in cosmetics?
Thymoquinone carries severe sensitization risk with documented case reports of SJS/TEN-mimicking reactions and confirmed allergenicity. No SCCS opinion or CIR monograph available; safety assessment burden falls entirely on individual assessor. The EU classifies Thymoquinone as "permitted". Safety rating: POOR.
Is Thymoquinone allowed in the EU?
Thymoquinone EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.
What does Thymoquinone do in cosmetics?
Thymoquinone functions as: Antioxidant, Antimicrobial, Anti-Inflammatory, Skin Conditioning. It is classified as a Antioxidant in our database. CAS number: 490-91-5.
What is the Margin of Safety for Thymoquinone?
not established The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.
Compliance Tools
Check Thymoquinone compliance across multiple jurisdictions:
Related Ingredients
Is Thymoquinone in Your Products?
Scan any product label with Piro — our free ingredient scanner. Point your camera at the ingredients list and get instant safety scores for every ingredient.
Try Piro Free →Analyze Your Full Ingredient List
Paste any INCI list into the Decoder for instant safety analysis, or calculate the Margin of Safety for Thymoquinone in your formulation.