Poor Cosmetic Ingredient SCCS/CIR Reviewed

Benzophenone-2

INCI: BENZOPHENONE-2

CAS Number
131-55-5
Function
UV filter, light stabilizer, fragrance
Safety Rating
POOR

Regulatory Status

๐Ÿ‡ช๐Ÿ‡บ EU Status permitted
๐Ÿ‡บ๐Ÿ‡ธ US Status permitted
US Notes Not an OTC sunscreen active; CIR concluded safe in 2021 at present practices (55 uses reported in VCRP)

For full compliance data across 55 jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety (MoS)
not established
Dermal Absorption
high
Sensitization
moderate

Calculate MoS for your specific formulation with the MoS Calculator.

Safety Opinions

Official safety assessments from the Scientific Committee on Consumer Safety (SCCS) and Cosmetic Ingredient Review (CIR).

sccs SCCS/1679/25 26 June 2025
Verdict: safe
NOAEL: 1239 mg/kg bw/day (oral)
Max Concentration: 5% in spray/aerosol

g the potential endocrine disrupting properties, the SCCS is of the opinion that BP-5 is safe when used as a UV filter up to a maximum concentration of 5% in sunscreen, face and hand cream, lipstick, sunscreen propellant spray and pump spray, when used separately or in combination (based on

sccs SCCS/1679/25 26 June 2025
Verdict: safe
NOAEL: 1239 mg/kg bw/day (oral)
Max Concentration: 5% in general

g the potential endocrine disrupting properties, the SCCS is of the opinion that BP-5 is safe when used as a UV filter up to a maximum concentration of 5% in sunscreen, face and hand cream, lipstick, sunscreen propellant spray and pump spray, when used separately or in combination (based on

sccs SCCS/1679/25 26 June 2025
Verdict: safe
NOAEL: 1239 mg/kg bw/day (oral)
Max Concentration: 10% in eye area

g the potential endocrine disrupting properties, the SCCS is of the opinion that BP-5 is safe when used as a UV filter up to a maximum concentration of 5% in sunscreen, face and hand cream, lipstick, sunscreen propellant spray and pump spray, when used separately or in combination (based on

Expert Verdict

Genotoxicity cannot be excluded; endocrine disruption confirmed; crosses BBB; high systemic availability; SCCS 2025 negative opinion. Likely candidate for future Annex II listing

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Concern Level: High

Regulatory Flags

fragrance-component eu_children_restricted ifra_fragrance

Frequently Asked Questions

Is Benzophenone-2 safe in cosmetics?

Genotoxicity cannot be excluded; endocrine disruption confirmed; crosses BBB; high systemic availability; SCCS 2025 negative opinion. Likely candidate for future Annex II listing The EU classifies Benzophenone-2 as "permitted". Safety rating: POOR. This ingredient has been reviewed by sccs.

Is Benzophenone-2 allowed in the EU?

Benzophenone-2 EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.

What does Benzophenone-2 do in cosmetics?

Benzophenone-2 functions as: UV filter, light stabilizer, fragrance. It is classified as a cosmetic ingredient in our database. CAS number: 131-55-5.

What is the Margin of Safety for Benzophenone-2?

not established The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.

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