Is Camphene safe in cosmetics?
Camphene has a safety rating of "EXCELLENT" in our database. EU status: permitted. US status: permitted.
Camphene
Also known as: 2,2-Dimethyl-3-methylenebicyclo[2.2.1]heptane, Bicyclo[2.2.1]heptane, 2,2-dimethyl-3-methylene-, Camphene (2,2-dimethyl-3-methylene-norbornane), 2,2-Dimethyl-3-methylenebicyclo(2.2.1)heptane, 3,3-Dimethyl-2-methylenenorcamphene (+6 more)
INCI: CAMPHENE
Camphene (CAS 79-92-5) is a cosmetic cosmetic ingredient functioning as Fragrance (perfuming agent); strong woody/piney scent. EU Regulation 1223/2009 status: permitted; GHS signal word WARNING. Industrial safety data is also available in the chemical safety database. Same-CAS public records also appear in industrial chemical safety, pharmaceutical, and food safety data.
View industrial chemical safety profile for CAS 79-92-5 →
Auto-generated CPSR Part A draft with source citations
Cross-Vertical Regulatory Divergence
Camphene is classified GHS Danger (H228, H304, H319, H400, H410, H401, H411, H226) in the chemicals database but is allowed in EU cosmetics.
Source: Cosmetics: ingredients.eu_status; Chemicals: ghs_classifications.signal_word/hazard_statement_code
Function
Fragrance (perfuming agent); strong woody/piney scent
Safety Rating
EXCELLENT
Chemistry & Identifiers
IUPAC Name
2,2-dimethyl-3-methylidenebicyclo[2.2.1]heptane
InChIKey
CRPUJAZIXJMDBK-UHFFFAOYSA-N
Regulatory Status
EU EU Status
permitted
US US Status
permitted
US Notes
FEMA GRAS 2229; FDA-approved food use under 21 CFR 172.515; no specific FDA cosmetic restrictions
For full compliance data across multiple jurisdictions, use the Substance Compliance tool.
Safety Data
Margin of Safety, dermal absorption, and sensitization profile summaries for Camphene.
Calculate MoS for your specific formulation with the MoS Calculator.
GHS Hazard Classification
Globally Harmonized System classification per ECHA C&L inventory and ILO/WHO International Chemical Safety Cards.
Signal Word
WARNING
Pictograms
FlamFlameEnviroAqua
Hazard Statements
Flammable solid Causes eye irritation Very toxic to aquatic life with long lasting effects
Short-term Exposure Effects
The substance is irritating to the eyes.
HRIPT Human Patch Test Studies
1 human repeat insult patch test aggregated from dermatological literature.
| Test Type | N | Sensitized | Dose µg/cm² | NESIL µg/cm² | Potency |
|---|---|---|---|---|---|
| HMT | - | 0 | 2592 | - | - |
ECHA REACH Registration
European Chemicals Agency REACH dossier and Substances of Very High Concern listing.
Registration Type
Full
Tonnage Band
100 - 1,000 tonnes
Substance Type
SUBSTANCE
SVHC Candidate
No
PubChem Annotations
Safety and regulatory annotations from PubChem (NCBI) aggregated sources.
Safety (2)
ICSC Safety Card
1704
Source: ILO-WHO International Chemical Safety Cards (ICSCs)
Skin Eye Respiratory Irritation
Contact can irritate the eyes and skin. Exposure can irritate the eyes, nose, and throat.
Source: Hazardous Substances Data Bank (HSDB)
Regulatory (2)
JECFA Number
1323
Source: Joint FAO/WHO Expert Committee on Food Additives (JECFA)
JECFA Evaluation
CAMPHENE | 2004 | No safety concern at current levels of intake when used as a flavouring agent | TRS 928-JECFA 63/64 | FAS 54-JECFA 63/235
Source: Joint FAO/WHO Expert Committee on Food Additives (JECFA)
Function Categories & List Membership
Cosmetic/Chemical Function Categories
Deodorizer
Dye
Flavouring and nutrient
Fragrance
No specific technical function
Regulatory List Membership (4)
IFRA Fragrance Transparency List
EPA Safer Chemical Ingredients List (SCIL)
FDA Substances Added to Food (EAFUS)
Consumer Product Chemical
Expert Verdict
Expert safety assessment and concern-level summary for Camphene.
Regulatory Flags
epa_safer_alternative
ifra_fragrance
fda_food_additive
jecfa_safe
NOAEL Studies Summary
View details ->Public NOAEL study rows linked to Camphene by CAS number or substance name.
Studies
3
Lowest NOAEL
250 mg/kg bw/day
Highest NOAEL
250 mg/kg bw/day
ECHA_REACH_reach_study_results_dossiers_23-05-2023.zip
Known Synonyms
2,2-Dimethyl-3-methylenebicyclo[2.2.1]heptane
Bicyclo[2.2.1]heptane, 2,2-dimethyl-3-methylene-
Camphene (2,2-dimethyl-3-methylene-norbornane)
2,2-Dimethyl-3-methylenebicyclo(2.2.1)heptane
3,3-Dimethyl-2-methylenenorcamphene
EINECS 201-234-8
EINECS 209-275-3
FEMA No. 2229
UNII-G3VG94Z26E
3,3-dimethyl-2-methylidenebicyclo[2.2.1]heptane
Comphene
Chemical Function
Fragrance
Deodorizer
No specific technical function
Flavouring and nutrient
Regulatory Lists
detected; Europe; Personal care - sexual wellness
detected; Europe; Personal care - sexual wellness
inert_ingredient; non_food_use; Pesticides
air; consumer_product; detected; emissions
air; Cleaning products and household care - laundry and fabric treatment; detected; emissions
air; detected; emissions; Personal care
air; Cleaning products and household care; detected; emissions
air; Cleaning products and household care - air freshener; detected; emissions
detected; Europe; Toys and children's products
air; detected; emissions; Europe; Other direct contact consumer goods
air; detected; emissions; Europe; Other direct contact consumer goods
air; detected; emissions; Europe; Other direct contact consumer goods
air; detected; emissions; Europe; Other direct contact consumer goods
air; detected; emissions; Europe; Other direct contact consumer goods
Cleaning products and household care - air freshener; Europe
air; Cleaning products and household care - air freshener; detected; emissions; Europe
detected; Europe; Personal care - sexual wellness
detected; Europe; Personal care - liniment
Australian Status
AICIS status: listed
Cross-Vertical Safety Context
Same-CAS public records found in pharmaceutical and food safety data.
SOURCE
ChEMBL / DrugCentral / FAERS
DB_PHARMA CAS match
Pharmaceutical Data
Same-CAS rows from the pharmaceutical spoke database.
Compound
CAMPHENE
ChEMBL ID
CHEMBL2268550
SOURCE
EFSA / FDA GRAS
food_additives
Food Safety Data
Same-CAS food additive or FDA GRAS records from the core public database.
Food Name
CAMPHENE
ADI
No safety concern at current levels of intake when used as a flavouring agent mg/kg bw
Food Category
flavoring
Frequently Asked Questions
Is Camphene allowed in the EU?
Camphene EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.
What does Camphene do in cosmetics?
Camphene functions as: Fragrance (perfuming agent); strong woody/piney scent. It is classified as a cosmetic ingredient in our database. CAS number: 79-92-5.
Is Camphene classified as hazardous under GHS?
Camphene carries a GHS signal word of "WARNING". Hazard statements: Flammable solid Causes eye irritation Very toxic to aquatic life with long lasting effects. This classification is based on the ILO/WHO International Chemical Safety Card and ECHA C&L inventory data. Note: GHS classification applies to the pure substance — at cosmetic use concentrations, hazard thresholds may not be met.
Is Camphene used outside cosmetics?
Camphene also appears in industrial chemical safety, pharmaceutical, and food safety data. The cross-vertical cards on this page render same-CAS public rows from the matched databases.
Does Camphene have different safety status in cosmetics vs industrial chemicals?
Camphene is classified GHS Danger (H228, H304, H319, H400, H410, H401, H411, H226) in the chemicals database but is allowed in EU cosmetics.
Compliance Tools
Check Camphene compliance across multiple jurisdictions:
Ingredient Decoder
Paste a full ingredient list for instant analysis
82 Allergen Checker
Check for EU declarable fragrance allergens
Substance Compliance
Check compliance across multiple jurisdictions
MoS Calculator
Calculate Margin of Safety using SCCS methodology
Heavy Metal Limits
Compare limits across jurisdictions
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