Good Fragrance Sensitization Data

Cinnamic Acid

INCI: CINNAMIC ACID

CAS Number
140-10-3
Function
Perfuming, Skin Conditioning
Safety Rating
GOOD

Regulatory Status

๐Ÿ‡ช๐Ÿ‡บ EU Status permitted
๐Ÿ‡บ๐Ÿ‡ธ US Status permitted
US Notes FEMA GRAS as flavoring. Permitted under RIFM/IFRA framework

For full compliance data across 55 jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety (MoS)
adequate
Dermal Absorption
high
Sensitization
none

Calculate MoS for your specific formulation with the MoS Calculator.

Sensitization Profile

Contact sensitization data for Cinnamic Acid based on clinical patch test studies and IFRA standards.

Sensitization Rate
low
Allergen Class
fragrance
EU Allergen Listed
yes
Patch Test Positive Rate
0.2%
Cross-reactivity Group
balsam-of-peru-group
Reaction Type
contact-dermatitis
IFRA Restricted

Source: EU 2023/1545; SCCS/1459/11

Expert Verdict

Cinnamic acid is unrestricted in EU with low risk at typical fragrance use levels. Significant dermal absorption up to 83.9% occluded requires consideration in cumulative exposure. Distinct from cinnamal which is an Annex III allergen.

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Concern Level: Low

Regulatory Flags

ifra_fragrance fda_food_additive jecfa_safe

Frequently Asked Questions

Is Cinnamic Acid safe in cosmetics?

Cinnamic acid is unrestricted in EU with low risk at typical fragrance use levels. Significant dermal absorption up to 83.9% occluded requires consideration in cumulative exposure. Distinct from cinnamal which is an Annex III allergen. The EU classifies Cinnamic Acid as "permitted". Safety rating: GOOD.

Is Cinnamic Acid allowed in the EU?

Cinnamic Acid EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.

What does Cinnamic Acid do in cosmetics?

Cinnamic Acid functions as: Perfuming, Skin Conditioning. It is classified as a Fragrance in our database. CAS number: 140-10-3.

What is the Margin of Safety for Cinnamic Acid?

adequate The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.

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