Is D&C Red No. 7 (CI 15850 safe in cosmetics?
D&C Red No. 7 (CI 15850 has a safety rating of "POOR" in our database. EU status: prohibited. US status: permitted.
Poor
Cosmetic Ingredient
D&C Red No. 7 (CI 15850
Also known as: 2-Naphthalenecarboxylic acid, 3-hydroxy-4-[(4-methyl-2-sulfophenyl)azo]-, calcium salt (1:1), Brilliant Carmine 6B, Lithol Rubine BCA, Calcium 3-hydroxy-4-[(4-methyl-2-sulfonatophenyl)diazenyl]naphthalene-2-carboxylate, 2-Naphthalenecarboxylic acid, 3-hydroxy-4-[2-(4-methyl-2-sulfophenyl)diazenyl]-, calcium salt (1:1) (+4 more)
INCI: D&C RED NO. 7
D&C Red No. 7 (CI 15850 (CAS 5281-04-9) is a cosmetic cosmetic ingredient functioning as Colorant. EU Regulation 1223/2009 status: prohibited, max 0.4%. Industrial safety data is also available in the chemical safety database. Same-CAS public records also appear in industrial chemical safety, pharmaceutical, and food safety data.
View industrial chemical safety profile for CAS 5281-04-9 →
Auto-generated CPSR Part A draft with source citations
Cross-Vertical Regulatory Divergence
D&C Red No. 7 (CI 15850 is prohibited in EU cosmetics at max 0.4% but has active industrial GHS classifications.
Source: Cosmetics: ingredients.eu_status/eu_max; Chemicals: ghs_classifications.signal_word
Regulatory Status
EU EU Status
prohibited
EU Max Conc.
0.4%
US US Status
permitted
For full compliance data across multiple jurisdictions, use the Substance Compliance tool.
Safety Data
Margin of Safety, dermal absorption, and sensitization profile summaries for D&C Red No. 7 (CI 15850.
Calculate MoS for your specific formulation with the MoS Calculator.
ECHA REACH Registration
European Chemicals Agency REACH dossier and Substances of Very High Concern listing.
Registration Type
Full
Tonnage Band
10,000 - 100,000 tonnes
Substance Type
SUBSTANCE
SVHC Candidate
No
Expanded Jurisdictional Detail
Additional regulatory detail beyond the 7-jurisdiction summary: Saudi SFDA, Korea MFDS, ASEAN ACD, Japan/Korea, Brazil/India, and cross-jurisdictional restriction entries.
Additional Jurisdictional Restrictions (1)
| Jurisdiction | Status | Max % | Product Type |
|---|---|---|---|
| BR | permitted_colorant | - | Column 3: Not near mucous membranes |
Additional Ingredient Properties
1 property record from structured ingredient metadata.
hair_dye
{"cas_number": "5281-04-9", "ingredient_class": "direct_dye", "color_index_CI_number": "15850:1", "chemical_class": "azo", "color_result_on_hair": "Red", "shade_range": "red", "primary_function": "direct_deposit", "requires_developer": "no", "deposit_only": "yes", "permanence": "temporary", "wash_fastness_shampoos": "1-4", "light_fastness": "moderate", "oxidation_mechanism": "direct_absorption", "…
Function Categories & List Membership
Cosmetic/Chemical Function Categories
Dye
Pigment
Regulatory List Membership (1)
FDA Indirect Food Contact Additives
Expert Verdict
Expert safety assessment and concern-level summary for D&C Red No. 7 (CI 15850.
Known Synonyms
2-Naphthalenecarboxylic acid, 3-hydroxy-4-[(4-methyl-2-sulfophenyl)azo]-, calcium salt (1:1)
Brilliant Carmine 6B
Lithol Rubine BCA
Calcium 3-hydroxy-4-[(4-methyl-2-sulfonatophenyl)diazenyl]naphthalene-2-carboxylate
2-Naphthalenecarboxylic acid, 3-hydroxy-4-[2-(4-methyl-2-sulfophenyl)diazenyl]-, calcium salt (1:1)
D & C Red No. 7
EINECS 226-109-5
3-Hydroxy-4-((2-sulfo-p-tolyl)azo)-2-naphthalenecarboxylic acid, calcium salt (1:1)
UNII-ECW0LZ41X8
Chemical Function
Dye
Pigment
Regulatory Lists
Europe; plastic_additive
Canada; Personal care; Substances in PCP - Canada (4/2014)
pharmaceutical
Personal care
Indirect additives food contact (10/2018)
Australian Status
AICIS status: listed
Cross-Vertical Safety Context
Same-CAS public records found in pharmaceutical and food safety data.
SOURCE
ChEMBL / DrugCentral / FAERS
DB_PHARMA CAS match
Pharmaceutical Data
Same-CAS rows from the pharmaceutical spoke database.
ChEMBL ID
CHEMBL2028348
SOURCE
EFSA / FDA GRAS
food_additives
Food Safety Data
Same-CAS food additive or FDA GRAS records from the core public database.
Food Name
Lithol Rubine BK / Pigment Rubine
E Number
E180
ADI
1.5 mg/kg bw
Food Category
colorant
Frequently Asked Questions
Is D&C Red No. 7 (CI 15850 allowed in the EU?
D&C Red No. 7 (CI 15850 EU regulatory status: prohibited. Maximum allowed concentration: 0.4%. This is based on EU Regulation 1223/2009 and its amendments.
What does D&C Red No. 7 (CI 15850 do in cosmetics?
D&C Red No. 7 (CI 15850 functions as: Colorant. It is classified as a cosmetic ingredient in our database. CAS number: 5281-04-9.
Is D&C Red No. 7 (CI 15850 used outside cosmetics?
D&C Red No. 7 (CI 15850 also appears in industrial chemical safety, pharmaceutical, and food safety data. The cross-vertical cards on this page render same-CAS public rows from the matched databases.
Does D&C Red No. 7 (CI 15850 have different safety status in cosmetics vs industrial chemicals?
D&C Red No. 7 (CI 15850 is prohibited in EU cosmetics at max 0.4% but has active industrial GHS classifications.
Compliance Tools
Check D&C Red No. 7 (CI 15850 compliance across multiple jurisdictions:
Ingredient Decoder
Paste a full ingredient list for instant analysis
82 Allergen Checker
Check for EU declarable fragrance allergens
Substance Compliance
Check compliance across multiple jurisdictions
MoS Calculator
Calculate Margin of Safety using SCCS methodology
Heavy Metal Limits
Compare limits across jurisdictions
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Good
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