Is Hydroxyectoin safe in cosmetics?
Hydroxyectoin has a safety rating of "EXCELLENT" in our database. EU status: permitted. US status: permitted.
EXCELLENT
Active Ingredient
Hydroxyectoin
INCI: HYDROXYECTOIN
Hydroxyectoin (CAS 81210-65-3) is a cosmetic active ingredient functioning as Hydroxylated analogue of ectoin; compatible solute from extremophilic bacteria. EU Regulation 1223/2009 status: permitted. Industrial safety data is also available in the chemical safety database.
View industrial chemical safety profile for CAS 81210-65-3 →
Function
Hydroxylated analogue of ectoin; compatible solute from extremophilic bacteria. Enhanced thermostability versus ectoin. Mechanism: stronger kosmotropic hydration shell formation providing superior protection at elevated temperatures, UV stress, osmotic extremes, and inflammatory challenges. Anti-inflammatory and barrier support. Used in heat-stress formulations and premium longevity skincare.
Editorial assessment
EXCELLENT
Preliminary editorial note — not a computed safety verdict.
Regulatory Status
EU EU Status
permitted
US US Status
permitted
US Notes
Permitted without restriction. Biotechnology-derived via fermentation. Premium longevity active with superior thermostability versus ectoin. MoCRA safety substantiation required.
For full compliance data across multiple jurisdictions, use the Substance Compliance tool.
Safety Data
Margin of Safety, dermal absorption, and sensitization profile summaries for Hydroxyectoin.
Calculate MoS for your specific formulation with the MoS Calculator.
Editorial summary
Preliminary editorial summary for Hydroxyectoin — not a computed safety verdict. See the sourced toxicological data above.
Regulatory Flags
longevity-skincare
biotech-derived
barrier-function
anti-inflammatory
uv-protection
thermostable
pollution-protection
Frequently Asked Questions
Is Hydroxyectoin allowed in the EU?
Hydroxyectoin EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.
What does Hydroxyectoin do in cosmetics?
Hydroxyectoin functions as: Hydroxylated analogue of ectoin; compatible solute from extremophilic bacteria. Enhanced thermostability versus ectoin. Mechanism: stronger kosmotropic hydration shell formation providing superior protection at elevated temperatures, UV stress, osmotic extremes, and inflammatory challenges. Anti-inflammatory and barrier support. Used in heat-stress formulations and premium longevity skincare.. It is classified as a Active Ingredient in our database. CAS number: 81210-65-3.
Compliance Tools
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Substance Compliance
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MoS Calculator
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Heavy Metal Limits
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