Excellent Active Ingredient

Hydroxypropyl Chitosan

INCI: HYDROXYPROPYL CHITOSAN

CAS Number
84069-44-3
Function
Film-forming polymer; conditioning agent; antimicrobial agent; wound-healing active
Safety Rating
EXCELLENT

Regulatory Status

๐Ÿ‡ช๐Ÿ‡บ EU Status permitted
๐Ÿ‡บ๐Ÿ‡ธ US Status permitted
US Notes Permitted cosmetic ingredient; chitin/chitosan biocompatibility extensively documented in medical device and wound dressing context; ECHA microplastics restriction exempt as natural biodegradable polymer; not individually GRAS-listed

For full compliance data across 55 jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety (MoS)
adequate
Dermal Absorption
negligible
Sensitization
none

Calculate MoS for your specific formulation with the MoS Calculator.

Expert Verdict

Excellent safety and sustainability profile with preferred biodegradable alternative to synthetic film formers, exempt from ECHA microplastics restriction and suitable for sensitive skin, wound-adjacent, and eco-certified formulations.

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Concern Level: None

Regulatory Flags

biodegradable natural-origin microplastics-exempt eco-preferred antimicrobial-properties

Frequently Asked Questions

Is Hydroxypropyl Chitosan safe in cosmetics?

Excellent safety and sustainability profile with preferred biodegradable alternative to synthetic film formers, exempt from ECHA microplastics restriction and suitable for sensitive skin, wound-adjacent, and eco-certified formulations. The EU classifies Hydroxypropyl Chitosan as "permitted". Safety rating: EXCELLENT.

Is Hydroxypropyl Chitosan allowed in the EU?

Hydroxypropyl Chitosan EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.

What does Hydroxypropyl Chitosan do in cosmetics?

Hydroxypropyl Chitosan functions as: Film-forming polymer; conditioning agent; antimicrobial agent; wound-healing active. It is classified as a Active Ingredient in our database. CAS number: 84069-44-3.

What is the Margin of Safety for Hydroxypropyl Chitosan?

adequate The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.

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Is Hydroxypropyl Chitosan in Your Products?

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