Regulatory Status
For full compliance data across 55 jurisdictions, use the Substance Compliance tool.
Safety Data
Calculate MoS for your specific formulation with the MoS Calculator.
Toxicological Studies
2 study endpoints found for Testosterone. NOAEL (No Observed Adverse Effect Level) values are used to calculate the Margin of Safety per SCCS methodology.
| Endpoint | Value | Route | Species | Study Type | Source |
|---|---|---|---|---|---|
| NOAEL | 2 mg/kg bw/day | 2400 | rat | other | REACH |
| NOEL | 2 mg/kg bw/day | 2400 | dog | other | REACH |
Expert Verdict
Endocrine disruptor; virilization risk; prohibited in cosmetics globally; pharmaceutical classification; any detection in a cosmetic product = adulteration
Regulatory Flags
Frequently Asked Questions
Is Testosterone safe in cosmetics?
Endocrine disruptor; virilization risk; prohibited in cosmetics globally; pharmaceutical classification; any detection in a cosmetic product = adulteration The EU classifies Testosterone as "prohibited". Safety rating: POOR. 2 toxicological study endpoint(s) are available in our database.
Is Testosterone allowed in the EU?
Testosterone EU regulatory status: prohibited. This is based on EU Regulation 1223/2009 and its amendments.
What does Testosterone do in cosmetics?
Testosterone functions as: Historical: skin conditioning / anti-aging (now pharmaceutical). It is classified as a cosmetic ingredient in our database. CAS number: 58-22-0.
What is the Margin of Safety for Testosterone?
not established The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.
What is the NOAEL for Testosterone?
The NOAEL (No Observed Adverse Effect Level) for Testosterone is 2 mg/kg bw/day based on a other study via 2400 route in rat. A total of 2 study endpoints are available. Source: REACH.
Compliance Tools
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Related Ingredients
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