Excellent Antioxidant Dermal Penetration

Lycopene Cosmetic

INCI: LYCOPENE

CAS Number
502-65-8
Function
Inhibits reactions promoted by oxygen, preventing oxidation and deterioration of both
Safety Rating
EXCELLENT

Regulatory Status

๐Ÿ‡ช๐Ÿ‡บ EU Status permitted
๐Ÿ‡บ๐Ÿ‡ธ US Status permitted
US Notes CIR assessments of carotenoid-containing botanicals (Rosa canina-derived ingredients) concluded the ingredients are safe when formulated to be non-irritating and non-sensitizing.

For full compliance data across 55 jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety (MoS)
not established
Dermal Absorption
negligible
Sensitization
none

Calculate MoS for your specific formulation with the MoS Calculator.

Dermal Penetration Profile

Skin absorption and penetration characteristics of Lycopene Cosmetic, relevant to systemic exposure and MoS calculations.

Absorption %
0.5-2%
Penetration Level
stratum-corneum
Penetration Depth
stratum corneum
Molecular Weight
536.9 Da
Log P
15.7
Systemic Absorption
minimal
Topical Bioavailability
0.2-1%
Safety Margin Factor
minimal
Vehicle Dependent
Yes โ€” absorption varies by formulation

Source: Exp Dermatol 2001

Expert Verdict

Lycopene has an excellent safety profile with no significant concerns identified.

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Concern Level: Low

Regulatory Flags

fda_food_additive eu_cosing_listed

Frequently Asked Questions

Is Lycopene Cosmetic safe in cosmetics?

Lycopene has an excellent safety profile with no significant concerns identified. The EU classifies Lycopene Cosmetic as "permitted". Safety rating: EXCELLENT.

Is Lycopene Cosmetic allowed in the EU?

Lycopene Cosmetic EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.

What does Lycopene Cosmetic do in cosmetics?

Lycopene Cosmetic functions as: Inhibits reactions promoted by oxygen, preventing oxidation and deterioration of both. It is classified as a Antioxidant in our database. CAS number: 502-65-8.

What is the Margin of Safety for Lycopene Cosmetic?

not established The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.

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