Regulatory Status
For full compliance data across 55 jurisdictions, use the Substance Compliance tool.
Safety Data
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Dermal Penetration Profile
Skin absorption and penetration characteristics of Zinc PCA, relevant to systemic exposure and MoS calculations.
Source: Int J Cosmet Sci 2012
Expert Verdict
Excellent multifunctional active for oily, acne-prone, and combination skin that targets sebum regulation, provides mild antimicrobial action, and contributes to keratinocyte health via zinc bioavailability with no safety concerns at typical use concentrations.
Regulatory Flags
Frequently Asked Questions
Is Zinc PCA safe in cosmetics?
Excellent multifunctional active for oily, acne-prone, and combination skin that targets sebum regulation, provides mild antimicrobial action, and contributes to keratinocyte health via zinc bioavailability with no safety concerns at typical use concentrations. The EU classifies Zinc PCA as "permitted". Safety rating: EXCELLENT.
Is Zinc PCA allowed in the EU?
Zinc PCA EU regulatory status: permitted. Maximum allowed concentration: 0.5–2%. This is based on EU Regulation 1223/2009 and its amendments.
What does Zinc PCA do in cosmetics?
Zinc PCA functions as: Sebum regulator; antimicrobial; astringent; humectant (PCA moiety); keratinocyte-supporting trace mineral; cofactor for superoxide dismutase and matrix metalloproteinases; acne-control active. It is classified as a Active Ingredient in our database. CAS number: 15454-75-8.
What is the Margin of Safety for Zinc PCA?
adequate The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.
Compliance Tools
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Related Ingredients
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