Regulatory Status
For full compliance data across 55 jurisdictions, use the Substance Compliance tool.
Safety Data
Calculate MoS for your specific formulation with the MoS Calculator.
Toxicological Studies
4 study endpoints found for Citronellol. NOAEL (No Observed Adverse Effect Level) values are used to calculate the Margin of Safety per SCCS methodology.
| Endpoint | Value | Route | Species | Study Type | Source |
|---|---|---|---|---|---|
| NOAEL | 1000 mg/kg bw/day | oral | mouse | oral | REACH |
| NOEL | >10000 ppm | oral | rat | oral | REACH |
| NOAEL | 2000 mg/kg bw/day | oral | rat | oral | REACH |
| NOEL | 51 mg/kg bw/day | oral | rat | oral | REACH |
Sensitization Profile
Contact sensitization data for Citronellol based on clinical patch test studies and IFRA standards.
Source: ESSCA/IVDK
Dermal Penetration Profile
Skin absorption and penetration characteristics of Citronellol, relevant to systemic exposure and MoS calculations.
Source: SCCS/1459/11, IFRA
Expert Verdict
EU declarable fragrance allergen with mandatory labelling requirements above specified thresholds. Moderate sensitization potential with IFRA restrictions. Commonly found in rose, geranium, and citronella oils.
Regulatory Flags
Frequently Asked Questions
Is Citronellol safe in cosmetics?
EU declarable fragrance allergen with mandatory labelling requirements above specified thresholds. Moderate sensitization potential with IFRA restrictions. Commonly found in rose, geranium, and citronella oils. The EU classifies Citronellol as "restricted". Safety rating: MODERATE. 4 toxicological study endpoint(s) are available in our database.
Is Citronellol allowed in the EU?
Citronellol EU regulatory status: restricted. Maximum allowed concentration: Declarable EU allergen; labelling required >10 ppm leave-on / >100 ppm rinse-off under Regulation (EU) 2023/1545; IFRA restrictions apply. This is based on EU Regulation 1223/2009 and its amendments.
What does Citronellol do in cosmetics?
Citronellol functions as: fragrance; antimicrobial. It is classified as a Fragrance in our database. CAS number: 106-22-9.
What is the Margin of Safety for Citronellol?
not established The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.
What is the NOAEL for Citronellol?
The NOAEL (No Observed Adverse Effect Level) for Citronellol is 1000 mg/kg bw/day based on a oral study via oral route in mouse. A total of 4 study endpoints are available. Source: REACH.
Compliance Tools
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Related Ingredients
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