Moderate Fragrance NOAEL Data GHS Classified

Linalyl Acetate

INCI: LINALYL ACETATE

CAS Number
115-95-7
Function
fragrance
Safety Rating
MODERATE

Regulatory Status

๐Ÿ‡ช๐Ÿ‡บ EU Status restricted
EU Max Conc. 0.001% (leave-on) / 0.01% (rinse-off) - declarable allergen under EU 2023/1545
๐Ÿ‡บ๐Ÿ‡ธ US Status permitted
US Notes Permitted; RIFM-assessed

For full compliance data across 55 jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety (MoS)
adequate
Dermal Absorption
high
Sensitization
high

Calculate MoS for your specific formulation with the MoS Calculator.

Toxicological Studies

6 study endpoints found for Linalyl Acetate. NOAEL (No Observed Adverse Effect Level) values are used to calculate the Margin of Safety per SCCS methodology.

Endpoint Value Route Species Study Type Source
NOAEL 250 mg/kg bw/day dermal rat dermal REACH
NOAEL 160 mg/kg bw/day oral rat oral REACH
NOAEL 250 mg/kg bw/day dermal - dermal REACH
NOAEL 117 mg/kg bw/day oral - oral REACH
NOAEL 200 mg/kg bw/day oral rat oral REACH
NOAEL 200 mg/kg bw/day oral - oral REACH

GHS Hazard Classification

Globally Harmonized System classification per ECHA C&L inventory and ILO/WHO International Chemical Safety Cards.

Signal Word
WARNING
Hazard Statements
Combustible liquid Causes eye irritation Toxic to aquatic life
Short-term Exposure Effects
The substance is mildly irritating to the eyes.

Expert Verdict

Major lavender constituent with low risk when fresh but oxidizes to potent contact allergens; newly individually declarable as EU allergen under EU 2023/1545 requiring separate declaration and label updates from July 2026; included in IFRA 51st Amendment restrictions.

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Concern Level: High

Regulatory Flags

allergen-eu sensitization-risk oxidation-sensitive ifra-restricted eu-labelling-required eu-2023-1545-newly-listed hydroperoxide-forming epa_safer_alternative ifra_fragrance fda_food_additive

Frequently Asked Questions

Is Linalyl Acetate safe in cosmetics?

Major lavender constituent with low risk when fresh but oxidizes to potent contact allergens; newly individually declarable as EU allergen under EU 2023/1545 requiring separate declaration and label updates from July 2026; included in IFRA 51st Amendment restrictions. The EU classifies Linalyl Acetate as "restricted". Safety rating: MODERATE. 6 toxicological study endpoint(s) are available in our database.

Is Linalyl Acetate allowed in the EU?

Linalyl Acetate EU regulatory status: restricted. Maximum allowed concentration: 0.001% (leave-on) / 0.01% (rinse-off) - declarable allergen under EU 2023/1545. This is based on EU Regulation 1223/2009 and its amendments.

What does Linalyl Acetate do in cosmetics?

Linalyl Acetate functions as: fragrance. It is classified as a Fragrance in our database. CAS number: 115-95-7.

What is the Margin of Safety for Linalyl Acetate?

adequate The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.

What is the NOAEL for Linalyl Acetate?

The NOAEL (No Observed Adverse Effect Level) for Linalyl Acetate is 250 mg/kg bw/day based on a dermal study via dermal route in rat. A total of 6 study endpoints are available. Source: REACH.

Is Linalyl Acetate classified as hazardous under GHS?

Linalyl Acetate carries a GHS signal word of "WARNING". Hazard statements: Combustible liquid Causes eye irritation Toxic to aquatic life. This classification is based on the ILO/WHO International Chemical Safety Card and ECHA C&L inventory data. Note: GHS classification applies to the pure substance โ€” at cosmetic use concentrations, hazard thresholds may not be met.

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