Cosmetic Ingredients with CIR Expert Panel Conclusions

The Cosmetic Ingredient Review (CIR) is a voluntary U.S. industry-funded expert panel that assesses the safety of cosmetic ingredients and publishes conclusions in the International Journal of Toxicology. CIR conclusions fall into several categories: "Safe as used" (no concentration restriction), "Safe with qualifications" (subject to specific conditions such as max concentration or product type), "Insufficient data to support safety", and "Unsafe". CIR operates independently of the FDA but its conclusions are widely referenced by cosmetic brands, regulators, and formulators globally. This cluster lists cosmetic ingredients with published CIR conclusions, showing the most recent assessment verdict and final report reference.