Regulatory Cluster
118 ingredients
Cosmetic Ingredients Listed Under California Proposition 65
California Proposition 65 (the Safe Drinking Water and Toxic Enforcement Act of 1986) requires businesses to warn Californians about significant exposures to chemicals that cause cancer, birth defects, or reproductive harm. The Office of Environmental Health Hazard Assessment (OEHHA) maintains the Prop 65 list and publishes No Significant Risk Levels (NSRLs) for carcinogens and Maximum Allowable Dose Levels (MADLs) for reproductive toxicants. A product containing a listed chemical above the safe harbor level must bear a Prop 65 warning. This cluster lists cosmetic ingredients currently on the Prop 65 list with their toxicity endpoint classifications and safe harbor values where published.
Functional Categories
Skin Conditioning Ingredients
Humectants in Cosmetics
Emollient Ingredients in Cosmetics
Antioxidants in Cosmetics
Surfactants in Cosmetics
Emulsifiers in Cosmetics
Fragrance Ingredients in Cosmetics
Cosmetic Colorants
Cosmetic Preservatives
UV Filters & Sunscreen Ingredients
Hair Conditioning Ingredients
Rheology Modifiers & Thickeners
Active Cosmetic Ingredients
Plant Extracts & Botanical Ingredients
Regulatory Clusters
Cosmetic Ingredients Flagged as Endocrine Disruptors
Cosmetic Ingredients Listed Under California Proposition 65
Cosmetic Ingredients with SCCS Safety Opinions
Cosmetic Ingredients with CIR Expert Panel Conclusions
Cosmetic Ingredients with GHS Hazard Classification
Cosmetic Ingredients with NOAEL Toxicological Data
Cosmetic Ingredients Banned or Restricted Globally
Cosmetic Ingredients with Sensitization Data
Cosmetic Ingredients with Dermal Absorption Data
Cosmetic Ingredients Restricted Under EU Regulation 1223/2009
Browse A-Z
| Ingredient | Safety | Toxicity Type |
|---|---|---|
| 2-Amino-4-Nitrophenol | Moderate | cancer |
| 2-Ethoxyethanol | Poor | developmental, male |
| 4,4'-ISOPROPYLIDENEDIPHENOL | Moderate | female |
| 4,4'-ISOPROPYLIDENEDIPHENOL | Moderate | developmental |
| 4,4'-Isopropylidenediphenol (Bisphenol A / BPA) | Poor | female |
| 4,4'-Isopropylidenediphenol (Bisphenol A / BPA) | Poor | developmental |
| 4-Amino-2-Nitrophenol ⚠️ | Poor | cancer |
| 4-Chloro-2-Aminophenol | Poor | cancer |
| ACETALDEHYDE | Moderate | cancer |
| ACETONYLACETONE | Good | male |
| ACRYLAMIDE | Moderate | cancer |
| ACRYLAMIDE | Moderate | developmental, male |
| ANILINE | Moderate | cancer |
| ANTHRAQUINONE | Moderate | cancer |
| Acetonylacetone (2,5-Hexanedione) | Poor | male |
| Androstenedione | Poor | cancer |
| Attapulgite | Moderate | cancer |
| Aziridine | Moderate | cancer |
| BHA | Good | cancer |
| BHA (Butylated Hydroxyanisole) | Moderate | cancer |
| Basic Violet 3 | Poor | cancer |
| Bergapten | Poor | cancer |
| Butadiene | Poor | cancer |
| Butadiene | Poor | developmental, female, male |
| Butyl Benzyl Phthalate | Poor | developmental |
| Butyl Benzyl Phthalate (BBP) | Poor | developmental |
| Butylated Hydroxyanisole | Good | cancer |
| CI 12010 (Sudan I / Solvent Yellow 14) | Poor | cancer |
| CI 12480 | Moderate | cancer |
| CI 15525 | Moderate | cancer |
| CI 42640 (FD&C Violet No. 1) | Poor | cancer |
| CI 77266 | Moderate | cancer |
| Caffeic Acid | Good | cancer |
| Captan | Moderate | cancer |
| Carbon Black | Moderate | cancer |
| Carrageenan | Good | cancer |
| Cyclohexanol | Good | male |
| DIBUTYL PHTHALATE | Moderate | developmental, female, male |
| DICHLOROMETHANE | Moderate | cancer |
| DIETHANOLAMINE | Moderate | cancer |
| DIETHYLHEXYL PHTHALATE | Moderate | cancer |
| DIETHYLHEXYL PHTHALATE | Moderate | developmental, male |
| Dibutyl Phthalate (DBP) | Poor | developmental, female, male |
| Dibutyl Phthalate (DBP) | Poor | developmental, female, male |
| Dichlorophene | Poor | developmental |
| Diethanolamine (DEA) | Poor | cancer |
| Diethanolamine (restrictions) | Good | cancer |
| Diethylhexyl Phthalate (DEHP) | Poor | cancer |
| Diethylhexyl Phthalate (DEHP) | Poor | cancer |
| Diethylhexyl Phthalate (DEHP) | Poor | developmental, male |
| Diethylhexyl Phthalate (DEHP) | Poor | developmental, male |
| Dihydroergotamine | Poor | developmental |
| Dimethyltolylamine | Poor | cancer |
| Disperse Blue 1 | Poor | cancer |
| ETHYLHEXYL ACRYLATE | Good | cancer |
| Epichlorohydrin | Poor | cancer |
| Epichlorohydrin | Poor | male |
| Estradiol | Poor | cancer |
| Ethinylestradiol | Poor | cancer |
| Ethoxyethanol (2-Ethoxyethanol) | Poor | developmental, male |
| Ethoxyethanol Acetate | Moderate | developmental, male |
| Ethylbenzene | Poor | cancer |
| Ethylene Dichloride | Poor | cancer |
| Ethylhexyl Acrylate (monomer) | Poor | cancer |
| Formaldehyde | Poor | cancer |
| GLYCOL | Good | developmental |
| Gemfibrozil | Poor | cancer |
| Gemfibrozil | Poor | female, male |
| Hexane | Poor | male |
| Isotretinoin Regulatory | Good | developmental |
| Lead Acetate | Poor | cancer |
| MIBK | Good | cancer |
| MIBK | Good | developmental |
| MIBK (Methyl Isobutyl Ketone) | Moderate | cancer |
| MIBK (Methyl Isobutyl Ketone) | Moderate | developmental |
| MYRCENE | Good | cancer |
| Methotrexate | Moderate | developmental |
| Methoxyethanol | Moderate | developmental, male |
| Methoxyethanol Acetate | Moderate | developmental, male |
| Methyl Alcohol | Moderate | developmental |
| Methyl Eugenol | Poor | cancer |
| Methyl Isopropyl Ketone | Moderate | developmental |
| Methyl Pyrrolidone | Moderate | developmental |
| Methylene Chloride | Poor | cancer |
| Methylrosanilinium Chloride | Moderate | cancer |
| NITROFURAZONE | Good | cancer |
| NITROMETHANE | Moderate | cancer |
| NITROUS OXIDE | Good | developmental, female |
| O-PHENYLPHENOL | Moderate | cancer |
| Phenolphthalein | Poor | cancer |
| Pigment Orange 5 | Good | cancer |
| Potassium Bromate | Poor | cancer |
| Progesterone | Poor | cancer |
| Propylene Glycol t-Butyl Ether | Moderate | cancer |
| Resmethrin | Poor | cancer |
| Resmethrin | Poor | developmental |
| Retinoic Acid (Tretinoin) Regulatory | Good | developmental |
| STYRENE | Moderate | cancer |
| Saccharin | Good | cancer |
| Sodium o-Phenylphenate | Poor | cancer |
| Spironolactone | Poor | cancer |
| Styrene (Monomer) | Poor | cancer |
| Styrene Oxide | Poor | cancer |
| Sulindac | Moderate | developmental, female |
| Testosterone | Poor | cancer |
| Thiourea ⚠️ | Poor | cancer |
| Thorium Dioxide | Poor | cancer |
| Toluene | Moderate | developmental |
| Toluene | Moderate | female |
| Toluene Cosmetic | Poor | developmental |
| Toluene Cosmetic | Poor | female |
| Topiramate | Poor | developmental |
| Tretinoin | Moderate | developmental |
| Valproic Acid | Poor | developmental |
| Vinyl Acetate | Moderate | cancer |
| Vinyl Chloride | Poor | cancer |
| Vinyl Cyclohexene Dioxide | Poor | cancer |
| Vinyl Cyclohexene Dioxide | Poor | female, male |