Regulatory Cluster 372 ingredients

Cosmetic Ingredients Banned or Restricted Globally

Cosmetic ingredient regulatory frameworks vary across jurisdictions: the EU uses a positive-list approach via Regulation 1223/2009 Annexes II through VI, the US FDA relies on a short list of prohibited substances at 21 CFR 700.11, Canada maintains a Cosmetic Ingredient Hotlist, Japan applies its MHLW standards for cosmetics, Korea publishes MFDS prohibited and restricted lists, ASEAN operates a harmonized cosmetic directive, and Australia regulates through the Poisons Standard (SUSMP) and Therapeutic Goods Act. An ingredient flagged in multiple jurisdictions represents a stronger consensus on safety concern than a single-jurisdiction flag. This cluster lists cosmetic ingredients restricted in 2 or more jurisdictions, sorted by jurisdiction count.

Functional Categories
Skin Conditioning Ingredients Humectants in Cosmetics Emollient Ingredients in Cosmetics Antioxidants in Cosmetics Surfactants in Cosmetics Emulsifiers in Cosmetics Fragrance Ingredients in Cosmetics Cosmetic Colorants Cosmetic Preservatives UV Filters & Sunscreen Ingredients Hair Conditioning Ingredients Rheology Modifiers & Thickeners Active Cosmetic Ingredients Plant Extracts & Botanical Ingredients
Regulatory Clusters
Cosmetic Ingredients Flagged as Endocrine Disruptors Cosmetic Ingredients Listed Under California Proposition 65 Cosmetic Ingredients with SCCS Safety Opinions Cosmetic Ingredients with CIR Expert Panel Conclusions Cosmetic Ingredients with GHS Hazard Classification Cosmetic Ingredients with NOAEL Toxicological Data Cosmetic Ingredients Banned or Restricted Globally Cosmetic Ingredients with Sensitization Data Cosmetic Ingredients with Dermal Absorption Data Cosmetic Ingredients Restricted Under EU Regulation 1223/2009
Browse A-Z
A B C D E F G H I J K L M N O P Q R S T U V W X Y Z #
Ingredient Safety Jurisdictions
DICHLOROMETHANE Moderate 7
Mercury Compounds Good 7
Methylene Chloride Poor 7
Vinyl Chloride Poor 7
ZIRCONIUM POWDER Moderate 7
Formaldehyde Poor 6
Hexachlorophene Moderate 6
ANILINE Moderate 5
Coal Tar Poor 5
DIETHYLHEXYL PHTHALATE Moderate 5
Diethylhexyl Phthalate (DEHP) Poor 5
Diethylhexyl Phthalate (DEHP) Poor 5
Hydroquinone Poor 5
Phenol Moderate 5
Retinoic Acid (Tretinoin) Regulatory Good 5
Tretinoin Moderate 5
2-Amino-4-Nitrophenol Moderate 4
2-Amino-5-Nitrophenol Moderate 4
2-NAPHTHOL Moderate 4
2-Naphthol (β-Naphthol) 🔴 Poor 4
4,4'-ISOPROPYLIDENEDIPHENOL Moderate 4
4,4'-Isopropylidenediphenol (Bisphenol A / BPA) Poor 4
4-Amino-2-Nitrophenol ⚠️ Poor 4
6-Aminocaproic Acid Moderate 4
ACRYLAMIDE Moderate 4
Acid Yellow 36 Poor 4
Basic Green 4 Poor 4
Basic Violet 1 Poor 4
Basic Violet 3 Poor 4
Butadiene Poor 4
Butane Good 4
CI 11725 Moderate 4
CI 12085 (Pigment Red 4 / D&C Red No. 36) Good 4
CI 12480 Moderate 4
CI 13065 (Acid Yellow 36 / Metanil Yellow / Ext. D&C Yellow No. 1) Poor 4
CI 42640 (FD&C Violet No. 1) Poor 4
Catalase Excellent 4
Catalase Cosmetic Ingredient Good 4
Chloroacetamide Poor 4
Chromium Moderate 4
Cydonia Oblonga Fruit Extract Excellent 4
DIBUTYL PHTHALATE Moderate 4
DMSO Moderate 4
DMSO (Dimethyl Sulfoxide) Poor 4
Datura Stramonium Extract Poor 4
Dibutyl Phthalate (DBP) Poor 4
Dibutyl Phthalate (DBP) Poor 4
Diethylene Glycol Poor 4
Dihydrocoumarin Good 4
Epichlorohydrin Poor 4
Ergocalciferol Moderate 4
Ethoxyethanol Acetate Moderate 4
Ethylene Dichloride Poor 4
Ethylhexyl Ethylhexanoate ⚠️ Good 4
HC Blue No. 4 Poor 4
Isobutane Excellent 4
MORPHOLINE Moderate 4
Methotrexate Moderate 4
Methoxyethanol Acetate Moderate 4
Methylrosanilinium Chloride Moderate 4
OXYQUINOLINE Moderate 4
Phenolphthalein Poor 4
Phenylacetonitrile Poor 4
Phosphorus Poor 4
Pigment Orange 5 Good 4
Pigment Red 4 Good 4
Potassium Bromate Poor 4
Sodium Pyrithione Moderate 4
Solvent Blue 35 Good 4
Solvent Red 24 Poor 4
Sparteine Poor 4
Spironolactone Poor 4
Thiram Poor 4
Toluene-2,6-Diamine Poor 4
Tricresyl Phosphate Poor 4
Urocanic Acid Moderate 4
2,4-Diamino-5-methylphenoxyethanol Moderate 3
2-Chloro-P-Phenylenediamine Poor 3
2-Ethoxyethanol Poor 3
2-Heptylidenecyclopentanone Moderate 3
2-Methoxymethyl-p-Aminophenol HCl Poor 3
2-Nitro-P-Phenylenediamine Poor 3
3-Benzylidene Camphor Poor 3
ACETALDEHYDE Moderate 3
ACID RED 27 Moderate 3
Acid Green 1 Moderate 3
Acid Red 184 Moderate 3
Acid Red 27 (Amaranth) Moderate 3
Acid Red 35 Poor 3
Acid Violet 9 Moderate 3
Adonia Vernalis Extract Poor 3
Aminoethylethanolamine Moderate 3
Ammi Majus Extract Moderate 3
Apocynum Cannabinum Root Extract Poor 3
Atranol Poor 3
Atropa Belladonna Root Extract Poor 3
Aziridine Moderate 3
Basic Blue 41 Poor 3
Basic Blue 7 Poor 3
Basic Blue 75 Moderate 3
Basic Green 1 Poor 3
Basic Red 22 Poor 3
Basic Violet 4 Moderate 3
Basic Yellow 11 Moderate 3
Basic Yellow 28 Moderate 3
Boric Acid Poor 3
Butyl Benzyl Phthalate Poor 3
Butyl Benzyl Phthalate (BBP) Poor 3
C13-15 Alkane Good 3
C18-21 Alkane Good 3
CHOLECALCIFEROL Poor 3
CI 10020 Moderate 3
CI 12010 (Sudan I / Solvent Yellow 14) Poor 3
CI 12370 (Pigment Red 112 / Permanent Red FGR) Moderate 3
CI 14700 (FD&C Red No. 4 / Red 4) Good 3
CI 15880 (D&C Red No. 34 / Pigment Red 63:1) Good 3
CI 16185 Moderate 3
CI 21100 Moderate 3
CI 21230 Moderate 3
CI 26100 Moderate 3
CI 42053 Good 3
CI 45190 Moderate 3
CI 45370 Good 3
CI 47000 Moderate 3
CI 51319 Good 3
CI 60725 Good 3
CI 73360 Good 3
CI 74160 Good 3
CI 74180 Good 3
Captan Moderate 3
Chloroatranol Poor 3
Choline Chloride Moderate 3
Cobalt Chloride Poor 3
Cyclotetrasiloxane Poor 3
D&C Red No. 30 (CI 73360) Good 3
DIETHANOLAMINE Moderate 3
Diethanolamine (DEA) Poor 3
Diethanolamine (restrictions) Good 3
Diisopropanolamine Good 3
Direct Blue 86 Moderate 3
Direct Red 81 Poor 3
Direct Yellow 12 Poor 3
Disperse Blue 1 Poor 3
Disperse Blue 3 Poor 3
Disperse Blue 7 Poor 3
Disperse Brown 1 Poor 3
Disperse Red 15 Poor 3
Disperse Violet 4 Poor 3
EVERNIA FURFURACEA EXTRACT Good 3
Ethoxyethanol (2-Ethoxyethanol) Poor 3
Ethyl Urocanate Poor 3
Evernia Prunastri Extract Good 3
Fast Green FCF Good 3
HC Blue No. 13 Moderate 3
HC Brown No. 1 Poor 3
HC Brown No. 2 Poor 3
HC Green No. 1 Poor 3
HC Orange No. 3 Moderate 3
HC Red No. 9 Poor 3
HC YELLOW NO. 3 Moderate 3
HC Yellow No. 6 Poor 3
HC Yellow No. 8 Poor 3
HYDROXYETHYLAMINOMETHYL-P-AMINOPHENOL Moderate 3
Hexane Poor 3
Hydroxyethylaminomethyl-p-Aminophenol HCl Poor 3
Hydroxylamine HCl Poor 3
Hydroxylamine Sulfate Poor 3
Hydroxyphenyl Dihydroxybenzamide Moderate 3
Isobutylparaben Poor 3
Isopropylparaben Good 3
Ketoconazole Good 3
Laurus Nobilis Leaf Extract Good 3
Laurus Nobilis Seed Oil Poor 3
Lead Acetate Poor 3
Lippia Alba Leaf/Stem Oil Moderate 3
Lippia Citriodora Flower/Leaf/Stem Oil Moderate 3
Lippia Citriodora Leaf Oil Moderate 3
Lobelia Inflata Extract Poor 3
METHYLENE DIPHENYL DIISOCYANATE Moderate 3
Methoxydiglycol Moderate 3
Methoxyethanol Moderate 3
Methyl Acetamide Moderate 3
Methyl Pyrrolidone Moderate 3
Methylene Diphenyl Diisocyanate (MDI) Moderate 3
Methylene Glycol Moderate 3
Minoxidil Moderate 3
N,N-DIETHYL-M-AMINOPHENOL Moderate 3
N,N-DIETHYL-M-AMINOPHENOL SULFATE Moderate 3
N,N-DIETHYL-P-PHENYLENEDIAMINE Moderate 3
N,N-DIMETHYL-P-PHENYLENEDIAMINE Moderate 3
N-VINYL PYRROLIDONE Moderate 3
O-Aminophenol Poor 3
OXYQUINOLINE SULFATE Moderate 3
PEG-3 2,2'-DI-P-PHENYLENEDIAMINE Good 3
Pentyl Dimethyl PABA Poor 3
Petrolatum Excellent 3
Phenylparaben Poor 3
Phytonadione Good 3
Pigment Red 112 Poor 3
Pigment Red 63:1 Good 3
Showing 200 of 372 ingredients. Search all 30,000+ ingredients
Ingredient Decoder
Paste any INCI list for instant analysis
Substance Compliance
Check compliance across multiple jurisdictions
MoS Calculator
Calculate Margin of Safety per SCCS methodology